SCHEMBL20529774

SCHEMBL20529774

CCCCC=CNC(C)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
SLC6A5 Q9Y345 1/20 0.49
F7 P08709 2/20 0.43
F3 P13726 2/20 0.43
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
TERT O14746 3/20 0.39
MAPT P10636 2/20 0.39
BLM P54132 2/20 0.39
HSD17B10 Q99714 2/20 0.39
FABP4 P15090 2/20 0.39
GMNN O75496 1/20 0.39
USP2 O75604 1/20 0.39
LMNA P02545 1/20 0.39
CYP1A2 P05177 1/20 0.39
POLB P06746 1/20 0.39
CYP2C9 P11712 1/20 0.39
ALOX15 P16050 1/20 0.39
APEX1 P27695 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20529773 1.00 FAAH (0.49) FAAHSMN1; SMN2SLC6A5F7F3
SCHEMBL20529775 1.00 FAAH (0.49) FAAHSMN1; SMN2SLC6A5F7F3
SCHEMBL20529766 1.00 FAAH (0.49) FAAHSMN1; SMN2SLC6A5F7F3
SCHEMBL20529780 0.95 FAAH (0.55) FAAHSMN1; SMN2SLC6A5F7F3
SCHEMBL20529761 0.95 FAAH (0.55) FAAHSMN1; SMN2SLC6A5F7F3
SCHEMBL20529769 0.95 FAAH (0.55) FAAHSMN1; SMN2SLC6A5F7F3
SCHEMBL20529767 0.95 FAAH (0.55) FAAHSMN1; SMN2SLC6A5F7F3
SCHEMBL17079547 0.93 FAAH (0.57) FAAHSMN1; SMN2SLC6A5F7F3
SCHEMBL17079549 0.93 FAAH (0.57) FAAHSMN1; SMN2SLC6A5F7F3
SCHEMBL17079556 0.93 FAAH (0.57) FAAHSMN1; SMN2SLC6A5F7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110506050-A Stable modulators of gamma C cytokine activity BIONIZ LLC 2019-11-26 CN claimed
US-12600757-B2 Peptides inhibiting gamma-c-cytokine activity and methods of use Bioniz Therapeutics, Inc. (US) 2026-04-14 US disclosed
US-20210324029-A1 STABLE MODULATORS OF GAMMA-C-CYTOKINE ACTIVITY Bioniz Therapeutics, Inc. 2021-10-21 US disclosed
EP-3606940-A1 STABLE MODULATORS OF GAMMA-C-CYTOKINE ACTIVITY Bioniz, LLC (US) 2020-02-12 EP disclosed
CN-110506050-A Stable modulators of gamma C cytokine activity BIONIZ LLC 2019-11-26 CN disclosed
WO-2018187499-A1 STABLE MODULATORS OF GAMMA-C-CYTOKINE ACTIVITY BIONIZ, LLC (US) 2018-10-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600757-B2 Peptides inhibiting gamma-c-cytokine activity and methods of use IL15, IL2, IL15RA FAAH 2241/4885SMN1; SMN2 606/4885SLC6A5 3634/4885
US-20210324029-A1 STABLE MODULATORS OF GAMMA-C-CYTOKINE ACTIVITY IL2, IL2RA, GMFG FAAH 4632/4885SMN1; SMN2 1305/4885SLC6A5 4338/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.