SCHEMBL17079556

SCHEMBL17079556

CCCCCC/C=C/N[C@H](C)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.57
SMN1; SMN2 Q16637 1/20 0.54
SLC6A5 Q9Y345 1/20 0.54
TERT O14746 3/20 0.49
PTPN1 P18031 3/20 0.49
PPARG P37231 3/20 0.49
PPARD Q03181 3/20 0.49
PPARA Q07869 3/20 0.49
MAPT P10636 2/20 0.49
BLM P54132 2/20 0.49
HSD17B10 Q99714 2/20 0.49
FABP4 P15090 2/20 0.49
GMNN O75496 1/20 0.49
USP2 O75604 1/20 0.49
LMNA P02545 1/20 0.49
CYP1A2 P05177 1/20 0.49
POLB P06746 1/20 0.49
CYP2C9 P11712 1/20 0.49
ALOX15 P16050 1/20 0.49
APEX1 P27695 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30361054 1.00 FAAH (0.57) FAAHSMN1; SMN2SLC6A5TERTPTPN1
SCHEMBL17079548 1.00 FAAH (0.57) FAAHSMN1; SMN2SLC6A5TERTPTPN1
SCHEMBL29425333 1.00 FAAH (0.57) FAAHSMN1; SMN2SLC6A5TERTPTPN1
SCHEMBL17079549 1.00 FAAH (0.57) FAAHSMN1; SMN2SLC6A5TERTPTPN1
SCHEMBL17079545 1.00 FAAH (0.57) FAAHSMN1; SMN2SLC6A5TERTPTPN1
SCHEMBL30361055 1.00 FAAH (0.57) FAAHSMN1; SMN2SLC6A5TERTPTPN1
SCHEMBL17079547 1.00 FAAH (0.57) FAAHSMN1; SMN2SLC6A5TERTPTPN1
SCHEMBL20529761 0.98 FAAH (0.55) FAAHSMN1; SMN2SLC6A5TERTPTPN1
SCHEMBL20529769 0.98 FAAH (0.55) FAAHSMN1; SMN2SLC6A5TERTPTPN1
SCHEMBL20529780 0.98 FAAH (0.55) FAAHSMN1; SMN2SLC6A5TERTPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4619021-A1 HER RECEPTOR DERIVED PEPTIDES AND METHODS OF USE THEREOF Ramot at Tel-Aviv University Ltd. (IL) 2025-09-24 EP claimed
CN-112119085-B Stabilizing peptide-mediated targeted protein degradation 丹娜-法伯癌症研究院有限公司 2025-04-01 CN claimed
WO-2025027389-A1 BIOLOGICALLY ACTIVE COMPOUNDS COMPRISING A STAPLED OR STITCHED PEPTIDE SUTURA THERAPEUTICS LIMITED (GB) 2025-02-06 WO claimed
WO-2024105656-A1 HER RECEPTOR DERIVED PEPTIDES AND METHODS OF USE THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2024-05-23 WO claimed
WO-2024069229-A2 BIOLOGICALLY ACTIVE COMPOUNDS SUTURA THERAPEUTICS LTD (GB) 2024-04-04 WO claimed
US-11944688-B2 Biologically active compounds SUTURA THERAPEUTICS LTD (GB) 2024-04-02 US claimed
WO-2024054892-A1 THERAPEUTIC PEPTIDES SHAPE THERAPEUTICS INC. (US) 2024-03-14 WO claimed
US-20230158166-A1 BIOLOGICALLY ACTIVE COMPOUNDS SUTURA THERAPEUTICS LTD (GB) 2023-05-25 US claimed
US-11541124-B2 Biologically active compound conjugated to a stapled or stitched peptide SUTURA THERAPEUTICS LTD (TC) 2023-01-03 US claimed
US-20220169688-A1 SELECTIVE TARGETING OF UBIQUITIN- AND UBIQUITIN-LIKE E1-ACTIVATING ENZYMES BY STRUCTURALLY-STABILIZED PEPTIDES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-06-02 US claimed
CN-114026113-A Selective targeting of ubiquitin and ubiquitin-like E1 activating enzymes by structurally stabilized peptides 丹娜法伯癌症研究院 2022-02-08 CN claimed
US-20210324029-A1 STABLE MODULATORS OF GAMMA-C-CYTOKINE ACTIVITY Bioniz Therapeutics, Inc. 2021-10-21 US claimed
EP-3737404-A1 SELECTIVE TARGETING OF APOPTOSIS PROTEINS BY STRUCTURALLY-STABILIZED AND/OR CYSTEINE-REACTIVE NOXA PEPTIDES Dana Farber Cancer Institute, Inc. (US) 2020-11-18 EP claimed
US-20200353092-A1 BIOLOGICALLY ACTIVE COMPOUND CONJUGATED TO A STAPLED OR STITCHED PEPTIDE SUTURA THERAPEUTICS LTD (TC) 2020-11-12 US claimed
WO-2020215005-A1 SELECTIVE TARGETING OF UBIQUITIN- AND UBIQUITIN-LIKE E1-ACTIVATING ENZYMES BY STRUCTURALLY-STABILIZED PEPTIDES DANA-FARBER CANCER INSTITUTE, INC. (US) 2020-10-22 WO claimed
US-10774114-B2 Respiratory syncytial virus (RSV) replication inhibitors FONDATION THE ARK (CH) 2020-09-15 US claimed
EP-3606940-A1 STABLE MODULATORS OF GAMMA-C-CYTOKINE ACTIVITY Bioniz, LLC (US) 2020-02-12 EP claimed
WO-2019118719-A1 SELECTIVE TARGETING OF APOPTOSIS PROTEINS BY STRUCTURALLY-STABILIZED AND/OR CYSTEINE-REACTIVE NOXA PEPTIDES DANA-FARBER CANCER INSTITUTE, INC. (US) 2019-06-20 WO claimed
WO-2018187499-A1 STABLE MODULATORS OF GAMMA-C-CYTOKINE ACTIVITY BIONIZ, LLC (US) 2018-10-11 WO claimed
WO-2018170299-A1 INHIBITORS OF PROKARYOTIC GENE TRANSCRIPTION AND USES THEREOF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2018-09-20 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11541124-B2 Biologically active compound conjugated to a stapled or stitched peptide BPGM, TMPO, SLC7A1 FAAH 4570/4885SMN1; SMN2 473/4885SLC6A5 449/4885
US-20200353092-A1 BIOLOGICALLY ACTIVE COMPOUND CONJUGATED TO A STAPLED OR STITCHED PEPTIDE BPGM, TMPO, SLC7A1 FAAH 4569/4885SMN1; SMN2 469/4885SLC6A5 448/4885
US-11944688-B2 Biologically active compounds BPGM, PICALM, TMPO FAAH 4637/4885SMN1; SMN2 623/4885SLC6A5 390/4885
US-20220169688-A1 SELECTIVE TARGETING OF UBIQUITIN- AND UBIQUITIN-LIKE E1-ACTIVATING ENZYMES BY STRUCTURALLY-STABILIZED PEPTIDES UBE2E1, MDM2, UBA1 FAAH 1879/4885SMN1; SMN2 1547/4885SLC6A5 4702/4885
US-20230158166-A1 BIOLOGICALLY ACTIVE COMPOUNDS BPGM, PICALM, TMPO FAAH 4637/4885SMN1; SMN2 623/4885SLC6A5 390/4885
US-20210324029-A1 STABLE MODULATORS OF GAMMA-C-CYTOKINE ACTIVITY IL2, IL2RA, GMFG FAAH 4632/4885SMN1; SMN2 1305/4885SLC6A5 4338/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.