Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20529938 | 0.82 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL8388332 | 0.76 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL8384298 | 0.75 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL212430 | 0.75 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL27469694 | 0.75 | PTGS1 (0.47) | PTGS2PTGS1 | |
| SCHEMBL8383829 | 0.74 | PTGS2 (0.75) | PTGS2PTGS1 | |
| SCHEMBL29177660 | 0.74 | PIK3CA (0.44) | — | |
| SCHEMBL8384808 | 0.73 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL27587375 | 0.71 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL27605223 | 0.68 | PTGS2 (0.55) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018187698-A2 | COMBINATION THERAPIES USING CASPASE-1 DEPENDENT ANTICANCER AGENTS AND PGE2 ANTAGONISTS | TRUSTEES OF TUFTS COLLEGE (US) | 2018-10-11 | — | — | WO | disclosed |