Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20529940 | 0.82 | PTGS2 (0.60) | PTGS2PTGS1 | |
| SCHEMBL19953393 | 0.79 | MAPK14 (0.51) | PTGS2PTGS1 | |
| SCHEMBL14198825 | 0.77 | IDO1 (0.46) | — | |
| SCHEMBL20529853 | 0.75 | PTGS1 (0.54) | PTGS2PTGS1 | |
| SCHEMBL6648605 | 0.73 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL8266066 | 0.73 | PTGS2 (0.63) | PTGS2PTGS1 | |
| SCHEMBL21113575 | 0.70 | PTGS1 (0.38) | PTGS2PTGS1 | |
| SCHEMBL215231 | 0.70 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL213644 | 0.70 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL28997882 | 0.66 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018187698-A2 | COMBINATION THERAPIES USING CASPASE-1 DEPENDENT ANTICANCER AGENTS AND PGE2 ANTAGONISTS | TRUSTEES OF TUFTS COLLEGE (US) | 2018-10-11 | — | — | WO | disclosed |