SCHEMBL2053006

SCHEMBL2053006

CCCC(=O)[C@@]1(O)[C@H](O)[C@@H](CO)O[C@@]1(C(=O)CCC)n1cnc2c(N)ncnc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 5/20 0.48
PI4KA P42356 2/20 0.44
PI4K2B Q8TCG2 2/20 0.44
PI4K2A Q9BTU6 2/20 0.44
PI4KB Q9UBF8 2/20 0.44
ADORA3 P0DMS8 6/20 0.44
SLC28A1 O00337 2/20 0.44
GMPS P49915 1/20 0.44
ADORA1 P30542 3/20 0.43
ADORA2B P29275 2/20 0.43
DPP4 P27487 1/20 0.43
MEN1 O00255 1/20 0.43
MAP3K7 O43318 1/20 0.43
SLC28A2 O43868 1/20 0.43
GAPDH P04406 1/20 0.43
MAPK1 P28482 1/20 0.43
STAT6 P42226 1/20 0.43
KMT2A Q03164 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
DOT1L Q8TEK3 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Calcium SCHEMBL5323177 0.99 ADORA2A (0.47) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL6849047 0.87 P2RY1 (0.50) ADORA1SMN1; SMN2
SCHEMBL10579698 0.86 ADORA2A (0.49) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL27710530 0.84 ADORA2A (0.44) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL10518099 0.83 ADORA2A (0.47) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL10346046 0.83 ADORA2A (0.47) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL6536153 0.82 PI4KA (0.46) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL27730980 0.81 ADORA2A (0.47) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL18953067 0.81 ADORA2A (0.42) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL4754458 0.81 HINT1 (0.44) ADORA3MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115960151-B Dibutyryl cyclophosphatidyl gland glycoside calcium and preparation method thereof 上海上药第一生化药业有限公司 2025-05-27 CN claimed
CN-116063364-B Preparation method of pharmaceutical grade dibutyryl adenosine cyclophosphate sodium 湖南尔康制药股份有限公司 2025-03-07 CN claimed
CN-119432923-A Method for inducing human spinal astrocytes to be converted into motor neurons 南通大学 2025-02-14 CN claimed
CN-117645643-B Synthesis method of sodium dibutyryl adenosine cyclophosphate 济南爱思医药科技有限公司 2024-12-27 CN claimed
CN-118786984-A Stem cell cold storage preservation solution and preparation method and application thereof 北京全式金生物技术股份有限公司 2024-10-18 CN claimed
CN-117919492-B Composite hydrogel dressing and preparation method thereof 辽宁志圣达生物科技有限公司 2024-08-27 CN claimed
CN-115873796-B Nerve cell combination and application thereof 中国科学院动物研究所 2024-05-14 CN claimed
CN-118006554-A Method for differentiating human dopaminergic neuron-like cells, differentiated cells and uses thereof 浙江大学 2024-05-10 CN claimed
CN-117919492-A Composite hydrogel dressing and preparation method thereof 辽宁志圣达生物科技有限公司 2024-04-26 CN claimed
CN-117866021-A Purification method of acylation liquid and preparation method of dibutyryl adenosine cyclophosphate 上海上药第一生化药业有限公司 2024-04-12 CN claimed
CN-106943421-A Application of the dibutyryl adenosine cyclophosphate salt in external application fat-eliminating slimming medicine is prepared 广州奕昕生物科技有限公司 2017-07-14 CN claimed
CN-105566424-B A kind of preparation method of Calcium Dibutyryladenosine Cyclophosph-ate 上海紫源制药有限公司 2017-04-05 CN claimed
CN-106478754-A The preparation method of 2 ' O only son's acyl adenosine cyclophosphate 上海上药第生化药业有限公司 2017-03-08 CN claimed
CN-105566424-A Method for preparing calcium dibutyryladenosine cyclophosphate Shanghai ziyuan pharmaceutical co ltd 2016-05-11 CN claimed
CN-105566423-A Method for purifying calcium dibutyryladenosine cyclophosphate Shanghai ziyuan pharmaceutical co ltd 2016-05-11 CN claimed
CN-104017040-A Preparation method and application of monobutyryl adenosine cyclophosphate or salt thereof SHANGHAI NO 1 BIOCHEMICAL & PHARMACEUTICAL CO LTD 2014-09-03 CN claimed
CN-100543029-C The preparation method of dibutyryl adenosine cyclophosphate HANGZHOU MEIYA PHARMACEUTICAL (CN) 2009-09-23 CN claimed
CN-101020708-A Process of preparing dibutyryl adenosine cyclophosphate HANGZHOU MEIYA PHARMACEUTICAL (CN) 2007-08-22 CN claimed
WO-2005054437-A2 COMPOSITIONS AND METHODS FOR EX VIVO PRESERVATION OF BLOOD VESSELS FOR VASCULAR GRAFTS USING INHIBITOR OF TYPE I AND/OR TYPE II PHOSPHODIESTERASES ST. CAMILLUS MEDICAL, INC. (US) 2005-06-16 WO claimed
CN-1593451-A Externally applied medicine for promoting male erection YANG XIHONG (CN) 2005-03-16 CN claimed