SCHEMBL6536153

SCHEMBL6536153

CCCC(=O)[C@@]1(n2cnc3c(N)ncnc32)O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 2/20 0.46
PI4K2B Q8TCG2 2/20 0.46
PI4K2A Q9BTU6 2/20 0.46
PI4KB Q9UBF8 2/20 0.46
ADORA3 P0DMS8 5/20 0.46
ADORA2A P29274 4/20 0.46
ADORA1 P30542 3/20 0.46
SLC28A1 O00337 2/20 0.46
ADORA2B P29275 2/20 0.46
DPP4 P27487 1/20 0.46
MEN1 O00255 1/20 0.46
MAP3K7 O43318 1/20 0.46
SLC28A2 O43868 1/20 0.46
GAPDH P04406 1/20 0.46
MAPK1 P28482 1/20 0.46
STAT6 P42226 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
DOT1L Q8TEK3 1/20 0.46
SLC29A1 Q99808 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL18486577 0.96 ADORA1 (0.45) PI4KAPI4K2BPI4K2API4KBADORA3
Pyrophosphoric Acid SCHEMBL18486634 0.93 ADORA1 (0.47) PI4KAPI4K2BPI4K2API4KBADORA3
SCHEMBL5561914 0.92 EHMT1 (0.46) PI4KAPI4K2BPI4K2API4KBADORA3
SCHEMBL27945755 0.92 EHMT1 (0.46) PI4KAPI4K2BPI4K2API4KBADORA3
SCHEMBL1066702 0.91 PI4KA (0.46) PI4KAPI4K2BPI4K2API4KBADORA3
SCHEMBL27653575 0.89 ADORA3 (0.48) PI4KAPI4K2BPI4K2API4KBADORA3
SCHEMBL6536432 0.88 ADORA3 (0.41) PI4KAPI4K2BPI4K2API4KBADORA3
SCHEMBL27927390 0.88 EHMT1 (0.42) PI4KAPI4K2BPI4K2API4KBADORA3
SCHEMBL219553 0.88 ADORA3 (0.49) PI4KAPI4K2BPI4K2API4KBADORA3
SCHEMBL28904753 0.87 PI4KA (0.46) PI4KAPI4K2BPI4K2API4KBADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-216653656-U Filter residue collection device is used in production of dibutyryl adenosine cyclophosphate sodium 济南倍生康医药化学有限公司 2022-06-03 CN claimed
CN-108997430-A Crystal of calcium dibutyryladenosine cyclophosphate 南京工业大学 2018-12-14 CN claimed
CN-105566424-B A kind of preparation method of Calcium Dibutyryladenosine Cyclophosph-ate 上海紫源制药有限公司 2017-04-05 CN claimed
CN-117645643-B Synthesis method of sodium dibutyryl adenosine cyclophosphate 济南爱思医药科技有限公司 2024-12-27 CN disclosed
CN-117866021-A Purification method of acylation liquid and preparation method of dibutyryl adenosine cyclophosphate 上海上药第一生化药业有限公司 2024-04-12 CN disclosed
CN-117645643-A Synthesis method of sodium dibutyryl adenosine cyclophosphate 济南爱思医药科技有限公司 2024-03-05 CN disclosed
CN-219231542-U Filter residue collection device for production of sodium dibutyryl adenosine cyclophosphate 济南爱思医药科技有限公司 2023-06-23 CN disclosed
CN-218794229-U Dibutyryl adenosine cyclophosphate sodium intermediate precipitation filtering dryer 济南爱思医药科技有限公司 2023-04-07 CN disclosed
CN-218794229-U Dibutyryl adenosine cyclophosphate sodium intermediate precipitation filtering dryer 济南爱思医药科技有限公司 2023-04-07 CN disclosed
CN-217288342-U Raw material preparation device is used in production of dibutyryl adenosine cyclophosphate sodium 济南倍生康医药化学有限公司 2022-08-26 CN disclosed
CN-216688092-U Dibutyryl adenosine cyclophosphate sodium preparation is with fermentation reation kettle 济南倍生康医药化学有限公司 2022-06-07 CN disclosed
CN-108997430-B Crystal of calcium dibutyryladenosine cyclophosphate 南京工业大学 2020-05-22 CN disclosed
CN-106478754-B The preparation method of 2 '-O- only son's acyl adenosine cyclophosphates 上海上药第一生化药业有限公司 2019-07-12 CN disclosed
CN-108997430-A Crystal of calcium dibutyryladenosine cyclophosphate 南京工业大学 2018-12-14 CN disclosed
CN-106478754-A The preparation method of 2 ' O only son's acyl adenosine cyclophosphate 上海上药第生化药业有限公司 2017-03-08 CN disclosed
CN-104017040-A Preparation method and application of monobutyryl adenosine cyclophosphate or salt thereof SHANGHAI NO 1 BIOCHEMICAL & PHARMACEUTICAL CO LTD 2014-09-03 CN disclosed
CN-104017040-A Preparation method and application of monobutyryl adenosine cyclophosphate or salt thereof SHANGHAI NO 1 BIOCHEMICAL & PHARMACEUTICAL CO LTD 2014-09-03 CN disclosed
CN-1675192-A Novel compounds, pharmaceutical compositions containing the same and methods of use of the same FASGEN INC (US) 2005-09-28 CN disclosed
EP-1466004-A1 PROCESS FOR THE SELECTIVE ENZYMATIC HYDROLYSIS OF NUCLEOSIDE POLYESTERS Innovate Biotechnology S.R.L. (IT) 2004-10-13 EP disclosed
WO-2003057894-A1 PROCESS FOR THE SELECTIVE ENZYMATIC HYDROLYSIS OF NUCLEOSIDE POLYESTERS INNOVATE BIOTECHNOLOGY S.R.L. (IT) 2003-07-17 WO disclosed