Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 5/20 | 0.48 |
| ▸ | CTSL | P07711 | 4/20 | 0.48 |
| ▸ | CTSK | P43235 | 4/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5708342 | 0.88 | HTT (0.56) | ALDH1A1LMNASMN1; SMN2HTTSYK | |
| SCHEMBL222634 | 0.88 | HTT (0.56) | ALDH1A1LMNASMN1; SMN2HTTSYK | |
| SCHEMBL5019087 | 0.88 | LMNA (0.61) | ALDH1A1LMNASMN1; SMN2HTTSYK | |
| SCHEMBL30642172 | 0.87 | LMNA (0.51) | ALDH1A1LMNASMN1; SMN2HTTSYK | |
| SCHEMBL223222 | 0.87 | LMNA (0.54) | ALDH1A1LMNASMN1; SMN2HTTSYK | |
| SCHEMBL20530485 | 0.86 | SYK (0.50) | ALDH1A1LMNASMN1; SMN2HTTSYK | |
| SCHEMBL20530450 | 0.86 | LMNA (0.57) | ALDH1A1LMNASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL19615746 | 0.86 | LMNA (0.52) | ALDH1A1LMNASMN1; SMN2HTTSYK | |
| SCHEMBL19615744 | 0.86 | LMNA (0.52) | ALDH1A1LMNASMN1; SMN2HTTSYK | |
| SCHEMBL5218083 | 0.85 | SYK (0.57) | ALDH1A1LMNASMN1; SMN2HTTSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200165640-A1 | FRUCTOSE-6-PHOSPHATE ALDOLASE VARIANTS FOR ALDOL CARBOLIGATIONS | SUSTAINABLE MOMENTUM, S.L. (ES) | 2020-05-28 | — | — | US | disclosed |
| CN-110945122-A | Fructose-6-phosphate aldolase variants for aldol condensation carbon linking | 西班牙高等科研理事会 | 2020-03-31 | — | — | CN | disclosed |
| EP-3388518-A1 | FRUCTOSE-6-PHOSPHATE ALDOLASE VARIANTS FOR ALDOL CARBOLIGATIONS | Consejo Superior de Investigaciones Cientificas (CSIC) (ES) | 2018-10-17 | — | — | EP | disclosed |