Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 12/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222634 | 1.00 | HTT (0.56) | HTTLMNASMN1; SMN2CASP1ALDH1A1 | |
| SCHEMBL5019087 | 0.91 | LMNA (0.61) | HTTLMNASMN1; SMN2ALDH1A1SYK | |
| SCHEMBL223222 | 0.90 | LMNA (0.54) | HTTLMNASMN1; SMN2CASP1ALDH1A1 | |
| SCHEMBL20530482 | 0.88 | ALDH1A1 (0.54) | HTTLMNASMN1; SMN2ALDH1A1SYK | |
| SCHEMBL19615746 | 0.88 | LMNA (0.52) | HTTLMNASMN1; SMN2CASP1ALDH1A1 | |
| SCHEMBL19615744 | 0.88 | LMNA (0.52) | HTTLMNASMN1; SMN2CASP1ALDH1A1 | |
| SCHEMBL30642172 | 0.87 | LMNA (0.51) | HTTLMNASMN1; SMN2CASP1ALDH1A1 | |
| SCHEMBL334682 | 0.86 | LMNA (0.56) | HTTLMNASMN1; SMN2ALDH1A1SYK | |
| SCHEMBL1569295 | 0.86 | LMNA (0.56) | HTTLMNASMN1; SMN2ALDH1A1SYK | |
| SCHEMBL12067897 | 0.86 | LMNA (0.56) | HTTLMNASMN1; SMN2ALDH1A1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220715-A1 | OXOINDOLINYL AMIDE DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| EP-1008590-B1 | Process for preparing optically active oxazolidinone derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2006-10-11 | — | — | EP | disclosed |
| US-6403804-B1 | ALLOWING HYDRAZINE TO REACT ON OPTICALLY ACTIVE ACID ESTER HAVING HYDROXYL GROUP AT 3-POSITION TO GIVE OPTICALLY ACTIVE HYDRAZIDE HAVING HYDROXYL GROUP AT 3-POSITION, SUBJECTING OPTICALLY ACTIVE HYDRAZIDE TO CURTIUS REARRANGEMENT | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-06-11 | — | — | US | disclosed |
| EP-1008590-A1 | Process for preparing optically active oxazolidinone derivative | Takasago International Corporation (JP) | 2000-06-14 | — | — | EP | disclosed |
| EP-0787718-B1 | Process for preparing optically active 4-hydroxy-2-pyrrolidone | TAKASAGO PERFUMERY CO LTD (JP) | 1999-09-08 | — | — | EP | disclosed |
| US-5837877-A | Process for preparing optically active 4-hydroxy-2-pyrrolidone | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1998-11-17 | — | — | US | disclosed |
| EP-0787718-A1 | Process for preparing optically active 4-hydroxy-2-pyrrolidone | Takasago International Corporation (JP) | 1997-08-06 | — | — | EP | disclosed |