Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.49 |
| ▸ | PPARD | Q03181 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17357094 | 0.88 | TUBB1 (0.49) | NQO1KDM1AFFAR1PPARDKDM4E | |
| SCHEMBL18361620 | 0.88 | TUBB1 (0.53) | NQO1FFAR1PPARDKDM4ECACNA1C | |
| SCHEMBL1510002 | 0.87 | KDM1A (0.45) | NQO1KDM1AFFAR1PPARDKDM4E | |
| SCHEMBL6349213 | 0.85 | KDM1A (0.46) | NQO1KDM1AFFAR1PPARDKDM4E | |
| SCHEMBL177773 | 0.85 | KDM1A (0.46) | NQO1KDM1AFFAR1PPARDKDM4E | |
| SCHEMBL1128493 | 0.83 | FFAR1 (0.59) | KDM1AFFAR1PPARD | |
| SCHEMBL1547853 | 0.83 | NQO1 (0.56) | NQO1FFAR1TDP1CACNA1CTSHR | |
| SCHEMBL11940790 | 0.82 | KDM1A (0.44) | NQO1KDM1AFFAR1PPARDKDM4E | |
| SCHEMBL16855936 | 0.82 | NQO1 (0.42) | NQO1KDM1AFFAR1PPARDKDM4E | |
| SCHEMBL6349214 | 0.82 | KDM1A (0.44) | NQO1KDM1AFFAR1PPARDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102241621-A | 5,5-disubstituted-2-iminopyrrolidine derivatives, preparation method thereof, and medical applications thereof | JIANGSU HENGRUI MEDICINE CO | 2011-11-16 | — | — | CN | disclosed |
| WO-2011064789-A1 | IMPROVED PROCESS FOR THE PREPARATION OF HALO-DIALKOXYBENZENES | HIKAL LIMITED (IN) | 2011-06-03 | — | — | WO | disclosed |
| US-7951305-B2 | Compound having hydrocoumarin skeleton, liquid crystal composition, and liquid crystal display device | CHISSO CORPORATION (JP) | 2011-05-31 | — | — | US | disclosed |
| US-20090267026-A1 | COMPOUND HAVING HYDROCOUMARIN SKELETON, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2009-10-29 | — | — | US | disclosed |
| EP-0922712-B1 | Novel electron donor containing compositions | UNION CARBIDE CHEM PLASTIC (US) | 2002-12-18 | — | — | EP | disclosed |
| EP-0922712-A1 | Novel electron donor containing compositions | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1999-06-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090267026-A1 | COMPOUND HAVING HYDROCOUMARIN SKELETON, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | HCN2, PIEZO1, TRPV4 | NQO1 2626/4885KDM1A 2972/4885FFAR1 3126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.