Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ABCB4 | P21439 | 1/20 | 0.34 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.34 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.33 |
| ▸ | IP6K3 | Q96PC2 | 2/20 | 0.33 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20533236 | 0.90 | LPAR1 (0.39) | LPAR1LPAR3LPAR2NR3C1NR3C2 | |
| SCHEMBL16060372 | 0.80 | LPAR1 (0.40) | LPAR1LPAR3LPAR2NR3C1NR3C2 | |
| SCHEMBL20533107 | 0.79 | LPAR1 (0.41) | LPAR1LPAR3LPAR2NR3C1NR3C2 | |
| SCHEMBL28597732 | 0.71 | ALDH1A1 (0.35) | LPAR1LPAR3LPAR2NR3C1NR3C2 | |
| SCHEMBL3784904 | 0.70 | LPAR1 (0.40) | LPAR1LPAR3LPAR2NR3C1NR3C2 | |
| SCHEMBL2761549 | 0.70 | TSHR (0.41) | LPAR1LPAR3LPAR2KDM4EMAPT | |
| SCHEMBL2761302 | 0.69 | RAB9A (0.42) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL2836880 | 0.69 | RAB9A (0.42) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL16061227 | 0.67 | LPAR1 (0.38) | LPAR1LPAR3LPAR2NR3C1NR3C2 | |
| SCHEMBL17324773 | 0.67 | BRD4 (0.41) | LPAR1KDM4EMAPTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105142635-B | Heterocyclic compounds useful for the treatment of diseases | 艾匹根生物技术有限公司 | 2021-07-27 | — | — | CN | disclosed |
| EP-2988743-B1 | HETEROCYCLIC COMPOUNDS USEFUL IN THE TREATMENT OF DISEASE | EPIGEN BIOSCIENCES INC (US) | 2020-12-09 | — | — | EP | disclosed |
| US-20180297962-A1 | Heterocyclic Compounds Useful In The Treatment of Disease | EPIGEN BIOSCIENCES, INC. (US) | 2018-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180297962-A1 | Heterocyclic Compounds Useful In The Treatment of Disease | LPAR1, LPAR4, LPAR2 | LPAR1 1/4885LPAR3 4/4885LPAR2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.