Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 13/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20534141 | 0.90 | PI4KB (0.47) | PI4KBLMNASMN1; SMN2MEN1MAPT | |
| SCHEMBL20533899 | 0.88 | PI4KB (0.61) | PI4KBLMNASMN1; SMN2MEN1MAPT | |
| SCHEMBL20533756 | 0.88 | PI4KB (0.54) | PI4KBJAK2JAK3PTK2ALDH1A1 | |
| SCHEMBL20533904 | 0.87 | PI4KB (0.60) | PI4KBLMNASMN1; SMN2MEN1MAPT | |
| SCHEMBL20534229 | 0.84 | PI4KB (0.59) | PI4KBLMNASMN1; SMN2MEN1MAPT | |
| SCHEMBL20533769 | 0.82 | PI4KB (0.54) | PI4KBJAK2JAK3PTK2ALDH1A1 | |
| SCHEMBL20533660 | 0.82 | PI4KB (0.35) | PI4KBLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL20533747 | 0.81 | PI4KB (0.63) | PI4KBLMNASMN1; SMN2MEN1MAPT | |
| SCHEMBL20534210 | 0.80 | PI4KB (0.54) | PI4KBSMN1; SMN2JAK2JAK3PTK2 | |
| SCHEMBL20533591 | 0.80 | DPP4 (0.41) | LMNASMN1; SMN2MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180298009-A1 | Fused Pyrazole Derivatives As Kinase Inhibitors | UCB BIOPHARMA SPRL (BE) | 2018-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180298009-A1 | Fused Pyrazole Derivatives As Kinase Inhibitors | PI4KA, PI4K2B, PI4KB | PI4KB 3/4885LMNA 4839/4885SMN1; SMN2 4769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.