Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20533670 | 0.90 | PI4KB (0.52) | PI4KBMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL20533591 | 0.84 | DPP4 (0.41) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL20533889 | 0.81 | PI4KB (0.48) | PI4KBSMN1; SMN2MAPTUSP2ALDH1A1 | |
| SCHEMBL20533594 | 0.80 | ALDH1A1 (0.36) | PI4KBLMNASMN1; SMN2MAPTUSP2 | |
| SCHEMBL21628162 | 0.80 | PI4KB (0.73) | PI4KBMEN1KMT2ALMNAMAPT | |
| SCHEMBL20533899 | 0.77 | PI4KB (0.61) | PI4KBMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL20533756 | 0.77 | PI4KB (0.54) | PI4KBALDH1A1HSD17B10CDK2 | |
| SCHEMBL20533904 | 0.76 | PI4KB (0.60) | PI4KBMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL20528890 | 0.72 | PI4KB (0.60) | PI4KBMEN1KMT2ALMNAMAPT | |
| SCHEMBL29644477 | 0.72 | PI4KB (0.60) | PI4KBMEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180298009-A1 | Fused Pyrazole Derivatives As Kinase Inhibitors | UCB BIOPHARMA SPRL (BE) | 2018-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180298009-A1 | Fused Pyrazole Derivatives As Kinase Inhibitors | PI4KA, PI4K2B, PI4KB | PI4KB 3/4885MEN1 3280/4885KMT2A 2326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.