Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.44 |
| ▸ | FLT3 | P36888 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | HTR2B | P41595 | 3/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29665008 | 1.00 | YTHDC1 (0.61) | YTHDC1ADORA3ADORA1FLT3NPC1 | |
| SCHEMBL18588088 | 0.85 | NPC1 (0.54) | YTHDC1FLT3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20533712 | 0.83 | YTHDC1 (0.59) | YTHDC1ADORA3ADORA1FLT3NPC1 | |
| SCHEMBL29664969 | 0.83 | YTHDC1 (0.59) | YTHDC1ADORA3ADORA1FLT3NPC1 | |
| SCHEMBL17902901 | 0.83 | YTHDC1 (0.79) | YTHDC1ADORA3ADORA1FLT3NPC1 | |
| SCHEMBL20533808 | 0.81 | YTHDC1 (0.67) | YTHDC1ADORA3ADORA1FLT3ADORA2A | |
| SCHEMBL29664968 | 0.81 | YTHDC1 (0.67) | YTHDC1ADORA3ADORA1FLT3ADORA2A | |
| SCHEMBL29664960 | 0.80 | YTHDC1 (0.59) | YTHDC1ADORA3ADORA1NPC1RAB9A | |
| SCHEMBL18587976 | 0.80 | YTHDC1 (0.59) | YTHDC1ADORA3ADORA1NPC1RAB9A | |
| SCHEMBL19010862 | 0.79 | YTHDC1 (0.73) | YTHDC1ADORA3ADORA1FLT3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3341371-B1 | ADENINE DERIVATIVES AND THEIR USE AS UV-PHOTOPROTECTIVE AGENTS | UNIV PALACKEHO (CZ) | 2022-06-29 | — | — | EP | claimed |
| US-20180298004-A1 | ADENINE DERIVATIVES AND THEIR USE AS UV-PHOTOPROTECTIVE AGENTS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2018-10-18 | — | — | US | claimed |
| EP-3341371-B1 | ADENINE DERIVATIVES AND THEIR USE AS UV-PHOTOPROTECTIVE AGENTS | UNIV PALACKEHO (CZ) | 2022-06-29 | — | — | EP | disclosed |
| US-10774084-B2 | Adenine derivatives and their use as UV-photoprotective agents | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2020-09-15 | — | — | US | disclosed |
| US-20180298004-A1 | ADENINE DERIVATIVES AND THEIR USE AS UV-PHOTOPROTECTIVE AGENTS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2018-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180298004-A1 | ADENINE DERIVATIVES AND THEIR USE AS UV-PHOTOPROTECTIVE AGENTS | XPA, ERCC4, UNG | YTHDC1 459/4885ADORA3 30/4885ADORA1 35/4885 |
| US-10774084-B2 | Adenine derivatives and their use as UV-photoprotective agents | XPA, ERCC4, UNG | YTHDC1 398/4885ADORA3 27/4885ADORA1 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.