Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.43 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | HTR2B | P41595 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20533712 | 1.00 | YTHDC1 (0.59) | YTHDC1ADORA3ADORA1FLT3NPC1 | |
| SCHEMBL18587527 | 0.86 | NPC1 (0.52) | YTHDC1FLT3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29664979 | 0.86 | NPC1 (0.52) | YTHDC1FLT3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29665008 | 0.83 | YTHDC1 (0.61) | YTHDC1ADORA3ADORA1FLT3NPC1 | |
| SCHEMBL20533803 | 0.83 | YTHDC1 (0.61) | YTHDC1ADORA3ADORA1FLT3NPC1 | |
| SCHEMBL29664972 | 0.82 | YTHDC1 (0.61) | YTHDC1ADORA3ADORA1FLT3NPC1 | |
| SCHEMBL18587078 | 0.82 | YTHDC1 (0.61) | YTHDC1ADORA3ADORA1FLT3NPC1 | |
| SCHEMBL17902901 | 0.81 | YTHDC1 (0.79) | YTHDC1ADORA3ADORA1FLT3NPC1 | |
| SCHEMBL18587965 | 0.80 | YTHDC1 (0.59) | YTHDC1ADORA3ADORA1NPC1RAB9A | |
| SCHEMBL29664961 | 0.80 | YTHDC1 (0.59) | YTHDC1ADORA3ADORA1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3341371-B1 | ADENINE DERIVATIVES AND THEIR USE AS UV-PHOTOPROTECTIVE AGENTS | UNIV PALACKEHO (CZ) | 2022-06-29 | — | — | EP | claimed |