⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8820028 | 0.68 | — | — | |
| SCHEMBL6013582 | 0.67 | — | — | |
| Sulfamide SCHEMBL12465683 | 0.63 | — | — | |
| SCHEMBL1415181 | 0.63 | — | — | |
| SCHEMBL27770207 | 0.63 | F2 (0.33) | — | |
| SCHEMBL692687 | 0.60 | LMNA (0.42) | — | |
| SCHEMBL3363038 | 0.60 | — | — | |
| Sulfamate SCHEMBL6525631 | 0.60 | — | — | |
| SCHEMBL5315226 | 0.60 | — | — | |
| SCHEMBL7013257 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130005803-A1 | USE OF COMPOUNDS IN THE TREATMENT OR PREVENTION OF SKIN DISORDERS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2013-01-03 | — | — | US | disclosed |
| EP-2512465-A1 | USE OF COMPOUNDS IN THE TREATMENT OR PREVENTION OF SKIN DISORDERS | Galderma Research & Development (FR) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011073248-A1 | USE OF COMPOUNDS IN THE TREATMENT OR PREVENTION OF SKIN DISORDERS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-06-23 | — | — | WO | disclosed |