Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6013582 | 0.72 | — | — | |
| SCHEMBL7581203 | 0.67 | F2 (0.36) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL28640678 | 0.63 | — | — | |
| SCHEMBL2053412 | 0.63 | — | — | |
| SCHEMBL23242 | 0.62 | — | — | |
| SCHEMBL21811 | 0.62 | — | — | |
| SCHEMBL75527 | 0.62 | — | — | |
| SCHEMBL27985624 | 0.62 | ALDH1A1 (0.47) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL24393027 | 0.62 | CA1 (0.32) | F2PRSS1PRSS2PRSS3CA1 | |
| SCHEMBL10351302 | 0.62 | F2 (0.37) | F2PRSS1PRSS2PRSS3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101646674-B | Indolobenzazepine derivatives for the treatment of hepatitis c | BRISTOL MYERS SQUIBB CO | 2013-05-29 | — | — | CN | disclosed |
| CN-101646674-A | The indoles and the benzoazepine derivative that are used for the treatment of hepatitis C | SQUIBB BRISTOL MYERS CO US | 2010-02-10 | — | — | CN | disclosed |