Dimethylamine

Dimethylamine

SCHEMBL20534296

CCC(Cc1ccc(C)cc1)C(=O)c1ccc(N2CCOCC2)cc1.CNC

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
MAPK1 P28482 2/20 0.52
TP53 P04637 1/20 0.52
PKM P14618 1/20 0.52
L3MBTL1 Q9Y468 2/20 0.48
GAA P10253 2/20 0.48
ALDH1A1 P00352 4/20 0.47
KDM4E B2RXH2 1/20 0.47
MAPT P10636 7/20 0.47
TDP1 Q9NUW8 2/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
ACACB O00763 1/20 0.46
AKR1C3 P42330 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
LMNA P02545 1/20 0.45
HIF1A Q16665 1/20 0.43
GSK3B P49841 1/20 0.43
CYP2D6 P10635 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3453765 0.96 NPC1 (0.52) NPC1RAB9AMAPK1TP53PKM
SCHEMBL28927708 0.92 MAPT (0.51) NPC1RAB9AMAPK1TP53PKM
Dimethylamine SCHEMBL28251025 0.90 SMN1; SMN2 (0.49) RAB9AL3MBTL1ALDH1A1MAPTMEN1
SCHEMBL30670623 0.88 MAPT (0.57) NPC1RAB9AMAPK1TP53PKM
SCHEMBL28110430 0.86 MAPT (0.46) NPC1RAB9AMAPK1TP53PKM
SCHEMBL13892504 0.86 SMN1; SMN2 (0.49) NPC1RAB9ATP53L3MBTL1ALDH1A1
SCHEMBL23610466 0.86 NPC1 (0.46) NPC1RAB9AMAPK1TP53PKM
SCHEMBL22721391 0.83 GSK3B (0.56) NPC1RAB9AMAPK1TP53PKM
SCHEMBL11033548 0.82 NPC1 (0.47) NPC1RAB9AMAPK1TP53PKM
SCHEMBL30419781 0.80 NPC1 (0.58) NPC1RAB9AMAPK1TP53PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110869849-A Method for improving light stability of flexible plate printing plate using flat top lattice point as characteristic 麦克德米德图像方案股份有限公司 2020-03-06 CN claimed
EP-3610327-A1 METHOD OF IMPROVING LIGHT STABILITY OF FLEXOGRAPHIC PRINTING PLATES FEATURING FLAT TOP DOTS Macdermid Graphics Solutions, LLC (US) 2020-02-19 EP claimed
US-20180297388-A1 Method of Improving Light Stability of Flexographic Printing Plates Featuring Flat Top Dots MACDERMID GRAPHICS SOLUTIONS, LLC 2018-10-18 US claimed