SCHEMBL11033548

SCHEMBL11033548

Cc1ccc(CC(CCN(C)C)C(=O)c2ccc(N3CCOCC3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
TP53 P04637 1/20 0.47
PKM P14618 1/20 0.47
MAPK1 P28482 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.44
GAA P10253 2/20 0.44
AKR1C3 P42330 1/20 0.43
ALDH1A1 P00352 3/20 0.43
KDM4E B2RXH2 1/20 0.43
MAPT P10636 6/20 0.43
TDP1 Q9NUW8 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
ACACB O00763 1/20 0.42
GSK3B P49841 1/20 0.41
LMNA P02545 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
POLB P06746 1/20 0.40
HIF1A Q16665 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28183752 0.90 AOC3 (0.41) NPC1RAB9ATP53PKMMAPK1
SCHEMBL2294354 0.90 MAPT (0.46) NPC1RAB9ATP53MAPK1L3MBTL1
SCHEMBL3453765 0.85 NPC1 (0.52) NPC1RAB9ATP53PKMMAPK1
SCHEMBL27771175 0.84 MAPT (0.45) NPC1RAB9ATP53L3MBTL1GAA
Dimethylamine SCHEMBL20534296 0.82 NPC1 (0.52) NPC1RAB9ATP53PKMMAPK1
SCHEMBL15453193 0.82 NPC1 (0.51) NPC1RAB9ATP53PKMMAPK1
SCHEMBL28205486 0.81 GAA (0.51) NPC1RAB9ATP53PKMMAPK1
SCHEMBL28927708 0.80 MAPT (0.51) NPC1RAB9ATP53PKMMAPK1
SCHEMBL23610466 0.80 NPC1 (0.46) NPC1RAB9ATP53PKMMAPK1
SCHEMBL27923385 0.79 MAPT (0.48) NPC1RAB9ATP53MAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110869849-A Method for improving light stability of flexible plate printing plate using flat top lattice point as characteristic 麦克德米德图像方案股份有限公司 2020-03-06 CN claimed
EP-3610327-A1 METHOD OF IMPROVING LIGHT STABILITY OF FLEXOGRAPHIC PRINTING PLATES FEATURING FLAT TOP DOTS Macdermid Graphics Solutions, LLC (US) 2020-02-19 EP claimed
US-20180297388-A1 Method of Improving Light Stability of Flexographic Printing Plates Featuring Flat Top Dots MACDERMID GRAPHICS SOLUTIONS, LLC 2018-10-18 US claimed
CN-108368367-A Radiation-curable ink-jet ink suitable for glass, ceramics or metal 图像电子公司 2018-08-03 CN claimed
WO-2020241728-A1 ADHESIVE COMPOSITION, OPTICAL COMPONENT, ELECTRONIC COMPONENT, AND ELECTRONIC MODULE 積水化学工業株式会社 2020-12-03 WO disclosed
WO-2020027298-A1 PHOTOCURABLE POWDER COATING COMPOSITION, COATING METHOD AND COATED ARTICLE KYB株式会社 2020-02-06 WO disclosed
CN-104062701-B The manufacturing method of polarizer 日东电工株式会社 2018-10-09 CN disclosed
CN-108368367-A Radiation-curable ink-jet ink suitable for glass, ceramics or metal 图像电子公司 2018-08-03 CN disclosed
US-20120190802-A1 POLYIMIDE POLYMER FROM NON-STOICHIOMETRIC COMPONENTS NEXOLVE CORPORATION (US) 2012-07-26 US disclosed