Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.79 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.59 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CLK1 | P49759 | 2/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 2/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.48 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.48 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.48 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20534545 | 1.00 | ALDH1A1 (0.79) | ALDH1A1CA9AKR1B1PSMB5GAA | |
| SCHEMBL20534546 | 1.00 | ALDH1A1 (0.79) | ALDH1A1CA9AKR1B1PSMB5GAA | |
| SCHEMBL20534417 | 0.89 | ALDH1A1 (0.63) | ALDH1A1CA9AKR1B1PSMB5LMNA | |
| SCHEMBL20534419 | 0.89 | ALDH1A1 (0.63) | ALDH1A1CA9AKR1B1PSMB5LMNA | |
| SCHEMBL20534342 | 0.89 | ALDH1A1 (0.63) | ALDH1A1CA9AKR1B1PSMB5LMNA | |
| SCHEMBL21783132 | 0.86 | ALDH1A1 (0.82) | ALDH1A1AKR1B1GAALMNAKDM4E | |
| SCHEMBL12177499 | 0.81 | ALDH1A1 (0.70) | ALDH1A1AKR1B1GAALMNAKDM4E | |
| SCHEMBL12177570 | 0.81 | ALDH1A1 (0.66) | ALDH1A1AKR1B1GAAKDM4EPOLB | |
| SCHEMBL12177719 | 0.80 | ALDH1A1 (0.65) | ALDH1A1AKR1B1GAAKDM4EPOLB | |
| SCHEMBL16223212 | 0.80 | ALDH1A1 (0.51) | ALDH1A1AKR1B1GAALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200068890-A1 | HETEROCYCLIC INHIBITORS OF LYSINE BIOSYNTHESIS VIA THE DIAMINOPIMELATE PATHWAY | LA TROBE UNIVERSITY (AU) | 2020-03-05 | — | — | US | disclosed |
| US-20200068890-A1 | HETEROCYCLIC INHIBITORS OF LYSINE BIOSYNTHESIS VIA THE DIAMINOPIMELATE PATHWAY | LA TROBE UNIVERSITY (AU) | 2020-03-05 | — | — | US | disclosed |
| EP-3609494-A1 | HETEROCYCLIC INHIBITORS OF LYSINE BIOSYNTHESIS VIA THE DIAMINOPIMELATE PATHWAY | La Trobe University (AU) | 2020-02-19 | — | — | EP | disclosed |
| CN-110621315-A | Heterocyclic inhibitors of lysine biosynthesis via the diaminopimelic acid pathway | 拉筹伯大学 | 2019-12-27 | — | — | CN | disclosed |
| WO-2018187845-A1 | HETEROCYCLIC INHIBITORS OF LYSINE BIOSYNTHESIS VIA THE DIAMINOPIMELATE PATHWAY | LA TROBE UNIVERSITY (AU) | 2018-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200068890-A1 | HETEROCYCLIC INHIBITORS OF LYSINE BIOSYNTHESIS VIA THE DIAMINOPIMELATE PATHWAY | DDC, ODC1, DDT | ALDH1A1 461/4885CA9 2233/4885AKR1B1 225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.