Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026479 | 0.97 | TSHR (0.67) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL29861938 | 0.94 | MEN1 (0.69) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL168645 | 0.94 | — | — | |
| SCHEMBL13625481 | 0.90 | MEN1 (0.73) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL237717 | 0.90 | — | — | |
| SCHEMBL2307153 | 0.90 | MEN1 (0.73) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL13096950 | 0.90 | MEN1 (0.52) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL12595181 | 0.90 | MEN1 (0.73) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL22144196 | 0.90 | MEN1 (0.73) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL7576909 | 0.90 | TSHR (0.67) | TSHRMAPK1MEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110573507-B | Small molecules | 邓迪大学 | 2023-11-14 | — | — | CN | disclosed |
| EP-3609889-B1 | SMALL MOLECULES | UNIV DUNDEE (GB) | 2023-07-05 | — | — | EP | disclosed |
| EP-3609889-B1 | SMALL MOLECULES | UNIV DUNDEE (GB) | 2023-07-05 | — | — | EP | disclosed |
| US-20220127257-A1 | SMALL MOLECULES | UNIVERSITY OF DUNDEE (GB) | 2022-04-28 | — | — | US | disclosed |
| US-20220127257-A1 | SMALL MOLECULES | UNIVERSITY OF DUNDEE (GB) | 2022-04-28 | — | — | US | disclosed |
| US-11261179-B2 | Small molecules | UNIVERSITY OF DUNDEE (GB) | 2022-03-01 | — | — | US | disclosed |
| US-20210163469-A1 | SMALL MOLECULES | UNIVERSITY OF DUNDEE (GB) | 2021-06-03 | — | — | US | disclosed |
| US-20210163469-A1 | SMALL MOLECULES | UNIVERSITY OF DUNDEE (GB) | 2021-06-03 | — | — | US | disclosed |
| EP-3609889-A1 | SMALL MOLECULES | University Of Dundee (GB) | 2020-02-19 | — | — | EP | disclosed |
| WO-2018189554-A1 | SMALL MOLECULES | UNIVERSITY OF DUNDEE (GB) | 2018-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127257-A1 | SMALL MOLECULES | ADRM1, MDM2, UBE2B | TSHR 3941/4885MAPK1 2900/4885MEN1 3139/4885 |
| US-11261179-B2 | Small molecules | ADRM1, MDM2, UBE2B | TSHR 3941/4885MAPK1 2900/4885MEN1 3139/4885 |
| US-20210163469-A1 | SMALL MOLECULES | ADRM1, MDM2, UBE2B | TSHR 3941/4885MAPK1 2900/4885MEN1 3139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.