Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20535701 | 0.84 | FFAR4 (0.43) | KMT2APOLBFFAR4ALDH1A1SMN1; SMN2 | |
| SCHEMBL21631981 | 0.82 | KMT2A (0.39) | KMT2APOLBFFAR4PPARGPPARA | |
| SCHEMBL21632010 | 0.81 | KMT2A (0.39) | KMT2APOLBFFAR4PPARGPPARA | |
| SCHEMBL20534677 | 0.79 | PTGFR (0.43) | KMT2ASMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL20534568 | 0.77 | KDM4E (0.42) | FFAR4PPARGALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL20534680 | 0.75 | PTGFR (0.43) | FFAR4SMN1; SMN2FFAR1 | |
| SCHEMBL25762423 | 0.74 | KMT2A (0.41) | KMT2APOLBALDH1A1GAASMN1; SMN2 | |
| SCHEMBL20534678 | 0.71 | KDM4E (0.43) | KMT2APOLBSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL3374542 | 0.71 | KMT2A (0.50) | KMT2APOLBPPARGPPARAALDH1A1 | |
| SCHEMBL20534596 | 0.71 | FFAR4 (0.41) | FFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609870-A1 | SUBSTITUTED N-ARYLETHYL-2-AMINOQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |
| WO-2018189012-A1 | SUBSTITUTED N-ARYLETHYL-2-AMINOQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-10-18 | — | — | WO | disclosed |