Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20535701 | 0.86 | FFAR4 (0.43) | PTGFRSMN1; SMN2FFAR4 | |
| SCHEMBL21631962 | 0.81 | PTGFR (0.46) | PTGFRPTGS2CTSAFFAR4FFAR1 | |
| SCHEMBL21632087 | 0.80 | PTGFR (0.39) | PTGFRPTGS2EPHX2CTSACTSS | |
| SCHEMBL20534568 | 0.79 | KDM4E (0.42) | PTGFRPTGS2SMN1; SMN2FFAR4 | |
| SCHEMBL20536700 | 0.78 | CNR2 (0.47) | PTGFREPHX2SMN1; SMN2FFAR4FFAR1 | |
| SCHEMBL19405291 | 0.77 | CTSS (0.40) | PTGS2AKR1C3AKR1C2CTSSSLC6A2 | |
| SCHEMBL20534638 | 0.75 | KMT2A (0.41) | SMN1; SMN2FFAR4FFAR1 | |
| SCHEMBL24106022 | 0.73 | P2RX7 (0.40) | EPHX2CTSS | |
| SCHEMBL20534596 | 0.73 | FFAR4 (0.41) | PTGFRFFAR4FFAR1 | |
| SCHEMBL4547921 | 0.72 | P2RX7 (0.42) | PTGS2AKR1C3AKR1C2CTSSSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609870-A1 | SUBSTITUTED N-ARYLETHYL-2-AMINOQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |
| WO-2018189012-A1 | SUBSTITUTED N-ARYLETHYL-2-AMINOQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-10-18 | — | — | WO | disclosed |