Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 3/20 | 0.43 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20535171 | 0.84 | LMNA (0.54) | KMT2AMEN1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL19304126 | 0.83 | MEN1 (0.38) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL20534572 | 0.81 | FFAR4 (0.45) | PTGFRSMN1; SMN2LMNA | |
| SCHEMBL21631921 | 0.80 | PTGFR (0.39) | PTGFRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL21632005 | 0.80 | PTGFR (0.46) | PTGFRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27613401 | 0.79 | CYSLTR2 (0.42) | LMNAL3MBTL1TSHR | |
| SCHEMBL20534638 | 0.79 | KMT2A (0.41) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL27728236 | 0.76 | CPA3 (0.45) | KMT2AMEN1SMN1; SMN2TSHR | |
| SCHEMBL18304343 | 0.76 | PTGS2 (0.47) | KMT2AMEN1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL22186816 | 0.76 | TSHR (0.50) | KMT2AMEN1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |
| WO-2018189011-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-10-18 | — | — | WO | disclosed |