⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26155014 | 0.82 | LMNA (0.30) | — | |
| SCHEMBL584593 | 0.81 | ANPEP (0.31) | — | |
| SCHEMBL23430890 | 0.81 | ANPEP (0.31) | — | |
| SCHEMBL15247177 | 0.77 | P2RX7 (0.30) | — | |
| SCHEMBL19236193 | 0.77 | P2RX7 (0.30) | — | |
| SCHEMBL28552954 | 0.77 | P2RX7 (0.30) | — | |
| SCHEMBL23190567 | 0.76 | — | — | |
| SCHEMBL24425414 | 0.76 | — | — | |
| SCHEMBL18760884 | 0.75 | — | — | |
| SCHEMBL18639301 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4702020-A1 | PYRIDOIMIDAZOLONE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF | Sanofi (FR) | 2026-03-04 | — | — | EP | disclosed |
| US-12415819-B2 | Cu- and Ni-catalyzed decarboxylative borylation reactions | THE SCRIPPS RESEARCH INSTITUTE (US) | 2025-09-16 | — | — | US | disclosed |
| US-12304907-B2 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2025-05-20 | — | — | US | disclosed |
| WO-2024223905-A1 | PYRIDOIMIDAZOLONE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2024-10-31 | — | — | WO | disclosed |
| US-20240279219-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2024-08-22 | — | — | US | disclosed |
| CN-110799193-B | Copper and nickel catalyzed decarboxylation borylation | 斯克利普斯研究院 | 2023-12-12 | — | — | CN | disclosed |
| CN-114786778-A | Therapeutic compounds | 基因泰克公司 | 2022-07-22 | — | — | CN | disclosed |
| US-20220024949-A1 | CU-AND NI-CATALYZED DECARBOXYLATIVE BORYLATION REACTIONS | THE SCRIPPS RESEARCH INSTITUTE | 2022-01-27 | — | — | US | disclosed |
| US-20220024949-A1 | CU-AND NI-CATALYZED DECARBOXYLATIVE BORYLATION REACTIONS | THE SCRIPPS RESEARCH INSTITUTE | 2022-01-27 | — | — | US | disclosed |
| US-11161859-B2 | Cu- and Ni-catalyzed decarboxylative borylation reactions | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-11-02 | — | — | US | disclosed |
| US-11161859-B2 | Cu- and Ni-catalyzed decarboxylative borylation reactions | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-11-02 | — | — | US | disclosed |
| CN-110799193-A | Copper and nickel catalyzed decarboxylation and boriding reactions | 斯克利普斯研究院 | 2020-02-14 | — | — | CN | disclosed |
| WO-2018189157-A1 | METHODS FOR PREPARING A BORONIC ACID OR A BORONIC ESTER | THE UNIVERSITY OF BRISTOL (GB) | 2018-10-18 | — | — | WO | disclosed |