Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | CTH | P32929 | 1/20 | 0.45 |
| ▸ | CBS | P35520 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81956 | 1.00 | HSD17B10 (0.46) | HSD17B10BLMPMP22TSHRCTH | |
| SCHEMBL14950228 | 1.00 | HSD17B10 (0.46) | HSD17B10BLMPMP22TSHRCTH | |
| SCHEMBL25495618 | 1.00 | HSD17B10 (0.46) | HSD17B10BLMPMP22TSHRCTH | |
| SCHEMBL6666413 | 1.00 | HSD17B10 (0.46) | HSD17B10BLMPMP22TSHRCTH | |
| SCHEMBL6664456 | 1.00 | HSD17B10 (0.46) | HSD17B10BLMPMP22TSHRCTH | |
| Hydrochloric Acid SCHEMBL8451150 | 0.97 | THRB (0.48) | HSD17B10BLMPMP22TSHRCTH | |
| SCHEMBL1277996 | 0.97 | HSD17B10 (0.44) | HSD17B10BLMPMP22TSHRCTH | |
| SCHEMBL3796484 | 0.97 | HSD17B10 (0.44) | HSD17B10BLMPMP22TSHRCTH | |
| SCHEMBL45305 | 0.97 | TSHR (0.47) | HSD17B10BLMPMP22TSHRCTH | |
| SCHEMBL25377946 | 0.93 | TSHR (0.45) | HSD17B10BLMPMP22TSHRCTH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117822319-A | Flame-retardant nylon yarn and preparation process thereof | 江苏九州纺织有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-110573507-B | Small molecules | 邓迪大学 | 2023-11-14 | — | — | CN | disclosed |
| EP-3609889-B1 | SMALL MOLECULES | UNIV DUNDEE (GB) | 2023-07-05 | — | — | EP | disclosed |
| US-20220127257-A1 | SMALL MOLECULES | UNIVERSITY OF DUNDEE (GB) | 2022-04-28 | — | — | US | disclosed |
| US-11261179-B2 | Small molecules | UNIVERSITY OF DUNDEE (GB) | 2022-03-01 | — | — | US | disclosed |
| US-20210163469-A1 | SMALL MOLECULES | UNIVERSITY OF DUNDEE (GB) | 2021-06-03 | — | — | US | disclosed |
| EP-3727355-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | AstraZeneca AB (SE) | 2020-10-28 | — | — | EP | disclosed |
| EP-3609889-A1 | SMALL MOLECULES | University Of Dundee (GB) | 2020-02-19 | — | — | EP | disclosed |
| US-20190194190-A1 | Compounds and Their Use in Treating Cancer | ASTRAZENECA PHARMACEUTICALS LP | 2019-06-27 | — | — | US | disclosed |
| WO-2018189554-A1 | SMALL MOLECULES | UNIVERSITY OF DUNDEE (GB) | 2018-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127257-A1 | SMALL MOLECULES | ADRM1, MDM2, UBE2B | HSD17B10 1202/4885BLM 1244/4885PMP22 3656/4885 |
| US-11261179-B2 | Small molecules | ADRM1, MDM2, UBE2B | HSD17B10 1202/4885BLM 1244/4885PMP22 3656/4885 |
| US-20190194190-A1 | Compounds and Their Use in Treating Cancer | F12, CCNY, CCNE1 | HSD17B10 2674/4885BLM 971/4885PMP22 3879/4885 |
| US-20210163469-A1 | SMALL MOLECULES | ADRM1, MDM2, UBE2B | HSD17B10 1202/4885BLM 1244/4885PMP22 3656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.