⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23225370 | 0.88 | TOP2A (0.34) | — | |
| SCHEMBL20534937 | 0.80 | DAGLB (0.32) | — | |
| SCHEMBL20534785 | 0.78 | POLB (0.40) | — | |
| SCHEMBL23965518 | 0.78 | POLB (0.40) | — | |
| SCHEMBL23211673 | 0.78 | POLB (0.35) | — | |
| SCHEMBL30932972 | 0.74 | RNASE1 (0.38) | — | |
| SCHEMBL20535903 | 0.72 | KDM1A (0.34) | — | |
| SCHEMBL22977554 | 0.72 | RNASE1 (0.39) | — | |
| SCHEMBL23225371 | 0.72 | RNASE1 (0.38) | — | |
| SCHEMBL22288090 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11161869-B2 | Thermally-cleavable protecting and linker groups | EVONETIX LTD. (GB) | 2021-11-02 | — | — | US | disclosed |
| US-20210107934-A1 | THERMALLY-CLEAVABLE PROTECTING AND LINKER GROUPS | SILICON VALLEY BANK | 2021-04-15 | — | — | US | disclosed |
| EP-3609866-A1 | THERMALLY-CLEAVABLE PROTECTING AND LINKER GROUPS | Evonetix Ltd (GB) | 2020-02-19 | — | — | EP | disclosed |
| WO-2018189546-A1 | THERMALLY-CLEAVABLE PROTECTING AND LINKER GROUPS | EVONETIX LTD (GB) | 2018-10-18 | — | — | WO | disclosed |