Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH5 | P11766 | 10/20 | 0.46 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30772967 | 1.00 | ADH5 (0.46) | ADH5CYP4Z1KDM4EALDH1A1HPGD | |
| SCHEMBL22077041 | 0.96 | ADH5 (0.46) | ADH5CYP4Z1KDM4EALDH1A1HPGD | |
| SCHEMBL22077998 | 0.95 | ADH5 (0.49) | ADH5CYP4Z1KDM4EALDH1A1HPGD | |
| SCHEMBL30772970 | 0.95 | ADH5 (0.49) | ADH5CYP4Z1KDM4ECYP3A4BAZ2B | |
| SCHEMBL20536593 | 0.95 | ADH5 (0.49) | ADH5CYP4Z1KDM4ECYP3A4BAZ2B | |
| SCHEMBL25492135 | 0.91 | CYP3A4 (0.50) | ADH5KDM4EALDH1A1HPGDCYP3A4 | |
| SCHEMBL20535813 | 0.88 | HTT (0.53) | ADH5KDM4EALDH1A1HPGDCYP3A4 | |
| SCHEMBL30772952 | 0.88 | HTT (0.53) | ADH5KDM4EALDH1A1HPGDCYP3A4 | |
| SCHEMBL22078000 | 0.85 | ADH5 (0.47) | ADH5CYP4Z1KDM4ETBXAS1MAPT | |
| SCHEMBL20536447 | 0.85 | TBXAS1 (0.48) | ADH5KDM4ETBXAS1PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609867-B1 | CARBAZOLE COMPOUNDS AND METHODS OF USE THEREOF | GSNO THERAPEUTICS INC (US) | 2024-05-15 | — | — | EP | disclosed |
| CN-110753683-B | Carbazole compounds and methods of use thereof | 吉斯诺治疗公司 | 2024-02-09 | — | — | CN | disclosed |
| US-11655244-B2 | Carbazole compounds and methods of use thereof | GSNO THERAPEUTICS, INC. (US) | 2023-05-23 | — | — | US | disclosed |
| US-11655244-B2 | Carbazole compounds and methods of use thereof | GSNO THERAPEUTICS, INC. (US) | 2023-05-23 | — | — | US | disclosed |
| US-11655244-B2 | Carbazole compounds and methods of use thereof | GSNO THERAPEUTICS, INC. (US) | 2023-05-23 | — | — | US | disclosed |
| US-20200181129-A1 | CARBAZOLE COMPOUNDS AND METHODS OF USE THEREOF | GSNO THERAPEUTICS, INC. | 2020-06-11 | — | — | US | disclosed |
| US-20200181129-A1 | CARBAZOLE COMPOUNDS AND METHODS OF USE THEREOF | GSNO THERAPEUTICS, INC. | 2020-06-11 | — | — | US | disclosed |
| EP-3609867-A1 | CARBAZOLE COMPOUNDS AND METHODS OF USE THEREOF | Saje Pharma, LLC (US) | 2020-02-19 | — | — | EP | disclosed |
| CN-110753683-A | Carbazole compounds and methods of use thereof | 赛吉制药有限责任公司 | 2020-02-04 | — | — | CN | disclosed |
| WO-2018191418-A1 | CARBAZOLE COMPOUNDS AND METHODS OF USE THEREOF | SAJE PHARMA, LLC (US) | 2018-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655244-B2 | Carbazole compounds and methods of use thereof | GSR, CBR3, CBR1 | ADH5 93/4885CYP4Z1 172/4885KDM4E 3228/4885 |
| US-20200181129-A1 | CARBAZOLE COMPOUNDS AND METHODS OF USE THEREOF | GSR, CBR3, CBR1 | ADH5 93/4885CYP4Z1 172/4885KDM4E 3228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.