SCHEMBL20536610

SCHEMBL20536610

CCO[Si](C)(C)c1cc(C)cc(OC)c1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
ACHE P22303 2/20 0.34
ELANE P08246 1/20 0.33
CYP3A4 P08684 2/20 0.32
PTPN1 P18031 1/20 0.32
HPGD P15428 1/20 0.32
TACR1 P25103 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
ESR1 P03372 2/20 0.30
AHR P35869 1/20 0.30
NPC1 O15118 1/20 0.30
MAPT P10636 1/20 0.30
RAB9A P51151 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3482537 0.85 MEN1 (0.31) ALDH1A1
SCHEMBL13027179 0.84 ALDH1A1 (0.36) ALDH1A1ACHEELANECYP3A4PTPN1
SCHEMBL3482283 0.73 CA1 (0.46) ALDH1A1ACHECYP3A4HPGDSMN1; SMN2
SCHEMBL13027077 0.71 ALDH1A1 (0.42) ALDH1A1ACHEELANECYP3A4PTPN1
SCHEMBL12817617 0.71 ALDH1A1 (0.42) ALDH1A1ACHEELANECYP3A4PTPN1
SCHEMBL13027861 0.71 ALDH1A1 (0.42) ALDH1A1ELANECYP3A4HPGDSMN1; SMN2
SCHEMBL13027205 0.71 ALDH1A1 (0.48) ALDH1A1ELANECYP3A4SMN1; SMN2ESR1
SCHEMBL17921293 0.70 ALDH1A1 (0.37) ALDH1A1ACHEELANECYP3A4PTPN1
SCHEMBL13027312 0.70 TACR1 (0.38) ALDH1A1ACHECYP3A4PTPN1HPGD
SCHEMBL3482397 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110520434-B Method for preparing arylalkoxysilanes by dehydrogenative silylation 美国陶氏有机硅公司 2022-08-23 CN claimed
EP-3609900-B1 METHOD FOR PREPARING ARYLALKOXYSILANES BY DEHYDROGENATIVE SILYLATION DOW SILICONES CORP (US) 2021-02-17 EP claimed
EP-3609900-A1 METHOD FOR PREPARING ARYLALKOXYSILANES BY DEHYDROGENATIVE SILYLATION Dow Silicones Corporation (US) 2020-02-19 EP claimed
WO-2018190999-A1 METHOD FOR PREPARING ARYLALKOXYSILANES BY DEHYDROGENATIVE SILYLATION DOW SILICONES CORPORATION (US) 2018-10-18 WO claimed
EP-3609900-B1 METHOD FOR PREPARING ARYLALKOXYSILANES BY DEHYDROGENATIVE SILYLATION DOW SILICONES CORP (US) 2021-02-17 EP disclosed
EP-3609900-A1 METHOD FOR PREPARING ARYLALKOXYSILANES BY DEHYDROGENATIVE SILYLATION Dow Silicones Corporation (US) 2020-02-19 EP disclosed
WO-2018190999-A1 METHOD FOR PREPARING ARYLALKOXYSILANES BY DEHYDROGENATIVE SILYLATION DOW SILICONES CORPORATION (US) 2018-10-18 WO disclosed