Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 9/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.37 |
| ▸ | KDM1A | O60341 | 4/20 | 0.36 |
| ▸ | MAOA | P21397 | 4/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20537553 | 1.00 | CYP3A4 (0.41) | CYP3A4MAPK1HCRTR2HCRTR1KDM1A | |
| SCHEMBL16796706 | 1.00 | CYP3A4 (0.41) | CYP3A4MAPK1HCRTR2HCRTR1KDM1A | |
| SCHEMBL16377487 | 0.84 | CYP3A4 (0.48) | CYP3A4MAPK1HCRTR2HCRTR1KDM1A | |
| SCHEMBL16339711 | 0.84 | CYP3A4 (0.48) | CYP3A4MAPK1HCRTR2HCRTR1KDM1A | |
| SCHEMBL1940012 | 0.84 | CYP3A4 (0.48) | CYP3A4MAPK1HCRTR2HCRTR1KDM1A | |
| SCHEMBL16339688 | 0.84 | CYP3A4 (0.48) | CYP3A4MAPK1HCRTR2HCRTR1KDM1A | |
| SCHEMBL13958487 | 0.84 | CYP3A4 (0.48) | CYP3A4MAPK1HCRTR2HCRTR1KDM1A | |
| SCHEMBL17821191 | 0.84 | CYP3A4 (0.48) | CYP3A4MAPK1HCRTR2HCRTR1KDM1A | |
| SCHEMBL16796708 | 0.77 | CYP3A4 (0.42) | CYP3A4MAPK1HCRTR2HCRTR1KDM1A | |
| SCHEMBL20537451 | 0.76 | CPB1 (0.34) | HCRTR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3079685-B1 | SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN | BIO PHARM SOLUTIONS CO LTD (KR) | 2018-11-28 | — | — | EP | claimed |
| EP-3079686-B1 | SULFAMATE DERIVATIVE COMPOUND FOR USE IN PREVENTING OR TREATING EPILEPSY | BIO PHARM SOLUTIONS CO LTD (KR) | 2018-10-24 | — | — | EP | claimed |