Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.68 |
| ▸ | KRAS | P01116 | 2/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20537805 | 1.00 | PTGS2 (0.68) | PTGS2KRASTRPV1ALDH1A1GLA | |
| SCHEMBL20538038 | 0.93 | PTGS2 (0.64) | PTGS2KRASTRPV1ALDH1A1GLA | |
| SCHEMBL20538041 | 0.93 | PTGS2 (0.64) | PTGS2KRASTRPV1ALDH1A1GLA | |
| SCHEMBL20537790 | 0.93 | PTGS2 (0.67) | PTGS2KRASTRPV1ALDH1A1MAPT | |
| SCHEMBL20537791 | 0.93 | PTGS2 (0.67) | PTGS2KRASTRPV1ALDH1A1MAPT | |
| SCHEMBL20538326 | 0.93 | PTGS2 (0.70) | PTGS2KRASTRPV1ALDH1A1MAPT | |
| SCHEMBL20538324 | 0.93 | PTGS2 (0.70) | PTGS2KRASTRPV1ALDH1A1MAPT | |
| SCHEMBL20538089 | 0.91 | TRPV1 (0.74) | PTGS2KRASTRPV1ALDH1A1GLA | |
| SCHEMBL20538500 | 0.90 | TUBB4A (0.63) | TRPV1ALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL20538498 | 0.90 | TUBB4A (0.63) | TRPV1ALDH1A1MAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3183230-B1 | N-((3,4,5-TRIMETHOXYSTYRYL)ARYL)CINNAMAMIDE COMPOUNDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2018-10-24 | — | — | EP | claimed |