Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.71 |
| ▸ | MMP2 | P08253 | 4/20 | 0.71 |
| ▸ | MMP9 | P14780 | 4/20 | 0.71 |
| ▸ | BCHE | P06276 | 1/20 | 0.64 |
| ▸ | KDM1A | O60341 | 4/20 | 0.61 |
| ▸ | BACE1 | P56817 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.57 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.57 |
| ▸ | TUBB | P07437 | 3/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.57 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.57 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.57 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20538432 | 1.00 | MMP1 (0.71) | MMP1MMP2MMP9BCHEKDM1A | |
| SCHEMBL20538260 | 0.95 | MMP1 (0.67) | MMP1MMP2MMP9BCHEKDM1A | |
| SCHEMBL20538259 | 0.95 | MMP1 (0.67) | MMP1MMP2MMP9BCHEKDM1A | |
| SCHEMBL20538622 | 0.94 | KDM1A (0.69) | MMP1MMP2MMP9BCHEKDM1A | |
| SCHEMBL20538620 | 0.94 | KDM1A (0.69) | MMP1MMP2MMP9BCHEKDM1A | |
| SCHEMBL20538554 | 0.93 | BCHE (0.74) | MMP1MMP2MMP9BCHEKDM1A | |
| SCHEMBL20538596 | 0.93 | MMP1 (0.67) | MMP1MMP2MMP9BCHEKDM1A | |
| SCHEMBL20538508 | 0.93 | MMP1 (0.67) | MMP1MMP2MMP9BCHEKDM1A | |
| SCHEMBL20538597 | 0.93 | MMP1 (0.67) | MMP1MMP2MMP9BCHEKDM1A | |
| SCHEMBL20538421 | 0.93 | ALDH1A1 (0.66) | MMP1MMP2MMP9BCHEKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3183230-B1 | N-((3,4,5-TRIMETHOXYSTYRYL)ARYL)CINNAMAMIDE COMPOUNDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2018-10-24 | — | — | EP | claimed |