SCHEMBL20540522

SCHEMBL20540522

CSCCC(N)C(=O)NC(Cc1ccc(F)cc1)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FNTA P49354 10/20 0.60
FNTB P49356 10/20 0.60
PGGT1B P53609 10/20 0.60
MME P08473 1/20 0.48
ALDH1A1 P00352 1/20 0.48
LTA4H P09960 1/20 0.47
CA2 P00918 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20540520 1.00 FNTA (0.60) FNTAFNTBPGGT1BMMEALDH1A1
SCHEMBL7609991 0.89 NPY1R (0.53) FNTAFNTBPGGT1BMME
SCHEMBL7609995 0.89 NPY1R (0.53) FNTAFNTBPGGT1BMME
SCHEMBL13154780 0.89 FNTA (0.60) FNTAFNTBPGGT1BMMELTA4H
SCHEMBL9442969 0.89 FNTA (0.60) FNTAFNTBPGGT1BMMELTA4H
SCHEMBL10696437 0.89 FNTA (0.60) FNTAFNTBPGGT1BMMELTA4H
SCHEMBL9442973 0.89 FNTA (0.60) FNTAFNTBPGGT1BMMELTA4H
SCHEMBL20540710 0.87 FNTA (0.48) FNTAFNTBPGGT1BMMELTA4H
SCHEMBL22503733 0.87 FNTA (0.57) FNTAFNTBPGGT1BALDH1A1
SCHEMBL20540709 0.87 FNTA (0.48) FNTAFNTBPGGT1BMMELTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11453699-B2 Antimicrobial compounds and/or modulators of microbial infections and methods of using the same INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2022-09-27 US disclosed
US-20210054025-A1 ANTIMICROBIAL COMPOUNDS AND/OR MODULATORS OF MICROBIAL INFECTIONS AND METHODS OF USING THE SAME UNIV INDIANA RES & TECH CORP (US) 2021-02-25 US disclosed
US-10793594-B2 Antimicrobial compounds and/or modulators of microbial infections and methods of using the same INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2020-10-06 US disclosed
US-20180305402-A1 ANTIMICROBIAL COMPOUNDS AND/OR MODULATORS OF MICROBIAL INFECTIONS AND METHODS OF USING THE SAME INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION 2018-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10793594-B2 Antimicrobial compounds and/or modulators of microbial infections and methods of using the same CD47, CGAS, FPR1 FNTA 439/4885FNTB 472/4885PGGT1B 827/4885
US-20180305402-A1 ANTIMICROBIAL COMPOUNDS AND/OR MODULATORS OF MICROBIAL INFECTIONS AND METHODS OF USING THE SAME CD47, CGAS, FPR1 FNTA 439/4885FNTB 472/4885PGGT1B 827/4885
US-11453699-B2 Antimicrobial compounds and/or modulators of microbial infections and methods of using the same CD47, CGAS, FPR1 FNTA 439/4885FNTB 472/4885PGGT1B 827/4885
US-20210054025-A1 ANTIMICROBIAL COMPOUNDS AND/OR MODULATORS OF MICROBIAL INFECTIONS AND METHODS OF USING THE SAME CD47, CGAS, FPR1 FNTA 439/4885FNTB 472/4885PGGT1B 827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.