Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 3/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | DRD3 | P35462 | 4/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13935054 | 0.90 | PDK2 (0.39) | PDK2ELANEPGRCYP2A6KDM1A | |
| SCHEMBL20542539 | 0.90 | PDK2 (0.39) | PDK2ELANEPGRCYP2A6TRPV4 | |
| SCHEMBL19186414 | 0.83 | PDK2 (0.37) | PDK2ELANEPGRALDH1A1CASP3 | |
| SCHEMBL15763512 | 0.81 | PDK2 (0.39) | PDK2PGRALDH1A1MEN1KMT2A | |
| SCHEMBL3206468 | 0.80 | TSHR (0.43) | PDK2PGRCYP2A6ALDH1A1DRD2 | |
| SCHEMBL4502871 | 0.80 | TSHR (0.43) | PDK2PGRCYP2A6ALDH1A1DRD2 | |
| SCHEMBL15763502 | 0.80 | PDK2 (0.40) | PDK2PGRALDH1A1MEN1KMT2A | |
| SCHEMBL20542545 | 0.79 | PDK2 (0.37) | PDK2ELANEPGRALDH1A1MEN1 | |
| SCHEMBL15763501 | 0.78 | PGR (0.43) | PDK2PGRMEN1KMT2A | |
| SCHEMBL17511218 | 0.77 | PGR (0.39) | PDK2ELANEPGRCYP2A6KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10113065-B1 | Two-photon absorbing compounds and methods of making same | GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE | 2018-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10113065-B1 | Two-photon absorbing compounds and methods of making same | TBXA2R, TBXAS1, TPD52L2 | PDK2 1206/4885ELANE 497/4885PGR 2136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.