Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | FAAH | O00519 | 2/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.56 |
| ▸ | TERT | O14746 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28682032 | 1.00 | TSHR (0.80) | TSHRALDH1A1FAAHTRPV1TERT | |
| SCHEMBL9066545 | 1.00 | TSHR (0.80) | TSHRALDH1A1FAAHTRPV1TERT | |
| SCHEMBL11745402 | 1.00 | TSHR (0.80) | TSHRALDH1A1FAAHTRPV1TERT | |
| SCHEMBL2634133 | 1.00 | TSHR (0.80) | TSHRALDH1A1FAAHTRPV1TERT | |
| SCHEMBL25178920 | 1.00 | TSHR (0.80) | TSHRALDH1A1FAAHTRPV1TERT | |
| SCHEMBL8852372 | 1.00 | TSHR (0.80) | TSHRALDH1A1FAAHTRPV1TERT | |
| SCHEMBL25181828 | 1.00 | TSHR (0.80) | TSHRALDH1A1FAAHTRPV1TERT | |
| SCHEMBL11745399 | 1.00 | TSHR (0.80) | TSHRALDH1A1FAAHTRPV1TERT | |
| SCHEMBL25181781 | 1.00 | TSHR (0.80) | TSHRALDH1A1FAAHTRPV1TERT | |
| SCHEMBL28656032 | 1.00 | TSHR (0.80) | TSHRALDH1A1FAAHTRPV1TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11471533-B2 | Compound usable as cationic lipid | KYOWA KIRIN CO., LTD. (JP) | 2022-10-18 | — | — | US | disclosed |
| EP-3521270-B1 | CATIONIC LIPID COMPOUND | KYOWA KIRIN CO LTD (JP) | 2022-06-29 | — | — | EP | disclosed |
| US-20210275672-A1 | COMPOUND USABLE AS CATIONIC LIPID | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2021-09-09 | — | — | US | disclosed |
| EP-3521270-A1 | CATIONIC LIPID COMPOUND | Kyowa Hakko Kirin Co., Ltd. (JP) | 2019-08-07 | — | — | EP | disclosed |
| US-20190008975-A1 | COMPOUND AS CATIONIC LIPID | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2019-01-10 | — | — | US | disclosed |
| EP-3395797-A1 | COMPOUNDS AS CATIONIC LIPIDS | Kyowa Hakko Kirin Co., Ltd. (JP) | 2018-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11471533-B2 | Compound usable as cationic lipid | NPC1L1, PLIN1, PLIN5 | TSHR 3958/4885ALDH1A1 3708/4885FAAH 869/4885 |
| US-20210275672-A1 | COMPOUND USABLE AS CATIONIC LIPID | NPC1L1, PLIN1, PLIN5 | TSHR 3958/4885ALDH1A1 3708/4885FAAH 869/4885 |
| US-20190008975-A1 | COMPOUND AS CATIONIC LIPID | NPC1L1, LIPA, CETP | TSHR 2967/4885ALDH1A1 2340/4885FAAH 323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.