Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 15/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD1 | P21728 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11670126 | 0.87 | ADRB2 (0.57) | ADRB3ADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL11750674 | 0.85 | ADRB2 (0.56) | ADRB3ADRB2ADRB1 | |
| SCHEMBL28529308 | 0.82 | ADRB2 (0.68) | ADRB3ADRB2DRD2DRD1DRD4 | |
| SCHEMBL10391023 | 0.80 | KDM4E (0.62) | ADRB3ADRB2DRD2DRD1DRD3 | |
| SCHEMBL2054517 | 0.76 | ADRB3 (0.63) | ADRB3ADRB2DRD2DRD1DRD3 | |
| Oxalic Acid SCHEMBL8596380 | 0.74 | ADRB2 (0.59) | ADRB3ADRB2DRD2DRD1DRD4 | |
| Oxalic Acid SCHEMBL8557358 | 0.74 | ADRB2 (0.59) | ADRB3ADRB2DRD2DRD1DRD4 | |
| SCHEMBL11672728 | 0.74 | ADRB2 (0.55) | ADRB3ADRB2DRD2DRD1DRD3 | |
| SCHEMBL8557913 | 0.74 | ADRB2 (0.65) | ADRB3ADRB2DRD2DRD1DRD4 | |
| SCHEMBL8557910 | 0.74 | ADRB2 (0.65) | ADRB3ADRB2DRD2DRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163758-B2 | Phenyl substituted pyrazinoylguanidine sodium channel blockers possessing beta agonist activity | PARION SCIENCES, INC. (US) | 2012-04-24 | — | — | US | disclosed |