Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 12/20 | 0.65 |
| ▸ | DRD2 | P14416 | 6/20 | 0.65 |
| ▸ | DRD3 | P35462 | 6/20 | 0.65 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.65 |
| ▸ | DRD1 | P21728 | 5/20 | 0.65 |
| ▸ | DRD4 | P21917 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MTOR | P42345 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557913 | 1.00 | ADRB2 (0.65) | ADRB2DRD2DRD3ADRB1DRD1 | |
| Oxalic Acid SCHEMBL8596380 | 0.94 | ADRB2 (0.59) | ADRB2DRD2DRD3ADRB1DRD1 | |
| Oxalic Acid SCHEMBL8557358 | 0.94 | ADRB2 (0.59) | ADRB2DRD2DRD3ADRB1DRD1 | |
| SCHEMBL28529308 | 0.91 | ADRB2 (0.68) | ADRB2DRD2DRD3ADRB1DRD1 | |
| Hexoprenaline SCHEMBL121449 | 0.85 | ADRB2 (0.72) | ADRB2DRD2DRD3ADRB1DRD1 | |
| Hexoprenaline SCHEMBL32668781 | 0.85 | ADRB2 (0.72) | ADRB2DRD2DRD3ADRB1DRD1 | |
| SCHEMBL3220388 | 0.84 | ADRB2 (0.61) | ADRB2DRD2DRD3ADRB1DRD1 | |
| SCHEMBL9768153 | 0.84 | ADRB2 (0.61) | ADRB2DRD2DRD3ADRB1DRD1 | |
| Hexoprenaline SCHEMBL3500862 | 0.83 | ADRB2 (0.70) | ADRB2DRD2DRD3ADRB1DRD1 | |
| Hexoprenaline SCHEMBL1604446 | 0.83 | ADRB2 (0.70) | ADRB2DRD2DRD3ADRB1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5775329-A | DERIVATIVES OF NOREPINEPHRINE USED TO STIMULATE EXERCISE STRESS AND ITS EFFECTS ON THE HEART. | GENSIA, INC. (US) | 1998-07-07 | — | — | US | claimed |
| EP-0833816-A1 | METHODS AND COMPOUNDS FOR DIAGNOSING CORONARY ARTERY DISEASE | GENSIA, INC. (US) | 1998-04-08 | — | — | EP | claimed |
| WO-1996040621-A1 | METHODS AND COMPOUNDS FOR DIAGNOSING CORONARY ARTERY DISEASE | GENSIA, INC. (US) | 1996-12-19 | — | — | WO | claimed |
| US-5775329-A | DERIVATIVES OF NOREPINEPHRINE USED TO STIMULATE EXERCISE STRESS AND ITS EFFECTS ON THE HEART. | GENSIA, INC. (US) | 1998-07-07 | — | — | US | disclosed |
| EP-0833816-A1 | METHODS AND COMPOUNDS FOR DIAGNOSING CORONARY ARTERY DISEASE | GENSIA, INC. (US) | 1998-04-08 | — | — | EP | disclosed |
| WO-1996040621-A1 | METHODS AND COMPOUNDS FOR DIAGNOSING CORONARY ARTERY DISEASE | GENSIA, INC. (US) | 1996-12-19 | — | — | WO | disclosed |