Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MPI | P34949 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18271562 | 0.85 | ALDH1A1 (0.58) | KDM4EMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL27919175 | 0.82 | ALDH1A1 (0.43) | KDM4EMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL24153139 | 0.81 | ALDH1A1 (0.55) | KDM4EMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL24550932 | 0.79 | ALDH1A1 (0.51) | KDM4EMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL20654841 | 0.78 | CYP11B1 (0.46) | KDM4EMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL14036884 | 0.76 | TSHR (0.48) | KDM4EHPGDMAPTTSHRTDP1 | |
| SCHEMBL25550065 | 0.76 | ALDH1A1 (0.49) | KDM4EMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL24949596 | 0.75 | ALDH1A1 (0.47) | KDM4EMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL28054478 | 0.75 | MEN1 (0.51) | KDM4EMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL8851574 | 0.75 | CYP1A2 (0.57) | KDM4EKMT2AHPGDALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615053-A1 | PHARMACEUTICAL COMPOSITION COMPRISING TRYPTOPHAN AND PHYLLOKININ DERIVATIVE FOR USE IN TREATING PSYCHIATRIC AND PSYCHOLOGICAL CONDITIONS | Temple Otorongo LLC (US) | 2020-03-04 | — | — | EP | claimed |
| WO-2018200381-A1 | PHARMACEUTICAL COMPOSITION COMPRISING TRYPTOPHAN AND PHYLLOKININ DERIVATIVE FOR USE IN TREATING PSYCHIATRIC AND PSYCHOLOGICAL CONDITIONS | TEMPLE OTORONGO LLC (US) | 2018-11-01 | — | — | WO | claimed |
| CN-103298772-B | Method for producing aromatic alcohol or heterocyclic aromatic alcohol | MITSUBISHI GAS CHEMICAL CO | 2015-06-24 | — | — | CN | disclosed |
| CN-103298772-A | Method for producing aromatic alcohol or heterocyclic aromatic alcohol | MITSUBISHI GAS CHEMICAL CO | 2013-09-11 | — | — | CN | disclosed |