Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20663065 | 0.77 | PTGS1 (0.58) | SQORPTGS1ESR2BACE1PDCD1 | |
| SCHEMBL4473036 | 0.77 | METAP2 (0.48) | TSHRSQORPTGS1ESR2BACE1 | |
| SCHEMBL20547712 | 0.76 | KDM4E (0.55) | TSHRTDP1NUDT1BRD4KDM4E | |
| SCHEMBL27412706 | 0.76 | TSHR (0.41) | TSHRTDO2ESR2TDP1BACE1 | |
| SCHEMBL26739579 | 0.75 | ESR2 (0.55) | TSHRTDO2ESR2TDP1BACE1 | |
| SCHEMBL26557606 | 0.75 | TSHR (0.44) | TSHRTDO2TDP1BACE1BRD4 | |
| SCHEMBL29131182 | 0.75 | HSD17B10 (0.57) | TSHRL3MBTL1KDM4EMAPTHPGD | |
| SCHEMBL18290888 | 0.75 | TSHR (0.55) | TSHRTDP1BRD4KDM4EHTT | |
| SCHEMBL3788714 | 0.74 | ALDH1A1 (0.48) | TSHRTDO2TDP1BACE1BRD4 | |
| SCHEMBL15856377 | 0.73 | METAP2 (0.46) | TSHRSQORPTGS1ESR2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1988144-A1 | ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL, ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE AND ILLUMINATING DEVICE | KONICA MINOLTA HOLDINGS, INC. (JP) | 2008-11-05 | — | — | EP | disclosed |