Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20547744 | 0.89 | MEN1 (0.34) | MEN1KMT2AHPGDADORA2AADORA2B | |
| SCHEMBL20548082 | 0.82 | TYMP (0.54) | ADORA1 | |
| SCHEMBL29973359 | 0.77 | HINT1 (0.55) | HPGDADORA2AADORA2BADORA3 | |
| SCHEMBL20547719 | 0.77 | STING1 (0.34) | — | |
| SCHEMBL31633414 | 0.76 | TYMP (0.48) | ADORA2AADORA3ADORA1 | |
| SCHEMBL20333315 | 0.75 | ADORA3 (0.66) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL4730570 | 0.74 | ADORA1 (0.53) | MEN1KMT2AADORA2AADORA2BADORA3 | |
| SCHEMBL29884403 | 0.74 | ADORA1 (0.53) | MEN1KMT2AADORA2AADORA2BADORA3 | |
| SCHEMBL7893460 | 0.74 | ADORA3 (0.68) | MEN1KMT2AADORA2AADORA2BADORA3 | |
| SCHEMBL7893467 | 0.74 | ADORA3 (0.68) | MEN1KMT2AADORA2AADORA2BADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018198084-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS WITH TRICYCLIC NUCLEOBASES | LUPIN LIMITED (IN) | 2018-11-01 | — | — | WO | disclosed |