Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pentylenetetrazol SCHEMBL1571876 | 0.81 | ALDH1A1 (0.69) | MEN1KMT2AALDH1A1MAPTBLM | |
| Pentylenetetrazol SCHEMBL22674 | 0.77 | ALDH1A1 (1.00) | MEN1KMT2AALDH1A1MAPTBLM | |
| SCHEMBL3182039 | 0.77 | ALDH1A1 (1.00) | MEN1KMT2AALDH1A1MAPTBLM | |
| Pentylenetetrazol SCHEMBL2260235 | 0.76 | ALDH1A1 (0.76) | MEN1KMT2AALDH1A1MAPTBLM | |
| Pentylenetetrazol SCHEMBL10408117 | 0.75 | ALDH1A1 (0.96) | MEN1KMT2AALDH1A1MAPTBLM | |
| Pentylenetetrazol SCHEMBL11463979 | 0.73 | MAPT (0.69) | MEN1KMT2AALDH1A1MAPTBLM | |
| (R)-3-Hydroxybutanoate SCHEMBL1533862 | 0.64 | SLC22A6 (0.56) | MAPTLMNA | |
| 3-Hydroxybutyric Acid, (+/-)- SCHEMBL1881926 | 0.64 | SLC22A6 (0.56) | MAPTLMNA | |
| 3-Hydroxybutyric Acid, (+/-)- SCHEMBL1897117 | 0.64 | SLC22A6 (0.56) | MAPTLMNA | |
| (R)-3-Hydroxybutanoate SCHEMBL29903959 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615084-A1 | MEMBRANE ACTIVE MOLECULES | Branequest, Inc. (US) | 2020-03-04 | — | — | EP | disclosed |
| WO-2018200412-A1 | MEMBRANE ACTIVE MOLECULES | BraneQuest, Inc. (US) | 2018-11-01 | — | — | WO | disclosed |