Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 7/20 | 0.51 |
| ▸ | CA1 | P00915 | 7/20 | 0.51 |
| ▸ | CA2 | P00918 | 7/20 | 0.51 |
| ▸ | CA9 | Q16790 | 7/20 | 0.51 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.43 |
| ▸ | RNF168 | Q8IYW5 | 1/20 | 0.42 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2098717 | 0.92 | CA12 (0.52) | CA12CA1CA2CA9ITGB1 | |
| SCHEMBL2099001 | 0.92 | CA12 (0.49) | CA12CA1CA2CA9ITGB1 | |
| SCHEMBL10025880 | 0.79 | CA12 (0.56) | CA12CA1CA2CA9ITGB1 | |
| SCHEMBL10025884 | 0.79 | CA12 (0.58) | CA12CA1CA2CA9ITGB1 | |
| SCHEMBL10025883 | 0.78 | CA12 (0.59) | CA12CA1CA2CA9ITGB1 | |
| SCHEMBL2054840 | 0.78 | MGMT (0.41) | — | |
| SCHEMBL11896715 | 0.77 | CA12 (0.59) | CA12CA1CA2CA9ITGB1 | |
| SCHEMBL14308477 | 0.74 | CA12 (0.72) | CA12CA1CA2CA9ITGB1 | |
| SCHEMBL19960611 | 0.74 | TDP1 (0.71) | CA12CA1CA2CA9ITGB1 | |
| SCHEMBL19960610 | 0.73 | TDP1 (0.70) | CA12CA1CA2CA9ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730298-B1 | SPECIFIC SUBSTRATES FOR O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE | EPFL ECOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (CH) | 2015-11-11 | — | — | EP | disclosed |
| US-8163479-B2 | Specific substrates for O6-alkylguanine-DNA alkyltransferase | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) | 2012-04-24 | — | — | US | disclosed |
| US-8163479-B2 | Specific substrates for O6-alkylguanine-DNA alkyltransferase | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) | 2012-04-24 | — | — | US | disclosed |
| US-20070243568-A1 | Specific Substrates for O6-Alkylguanine-Dna Alkyltransferase | EPFL ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) | 2007-10-18 | — | — | US | disclosed |
| US-20070243568-A1 | Specific Substrates for O6-Alkylguanine-Dna Alkyltransferase | EPFL ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070243568-A1 | Specific Substrates for O6-Alkylguanine-Dna Alkyltransferase | AGT, AGXT, AGTR1 | CA12 4578/4885CA1 4500/4885CA2 3221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.