SCHEMBL20548849

SCHEMBL20548849

C=CC(=O)Nc1cc(Nc2cc(Nc3cc(C(F)(F)F)ccc3F)ncn2)c(OC)cc1N(C)CC(C)(C)N

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
EGFR P00533 19/20 0.53
ALK Q9UM73 6/20 0.44
EML4 Q9HC35 5/20 0.44
CDK4 P11802 1/20 0.43
CDK2 P24941 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20548850 0.89 EGFR (0.66) EGFRALKEML4
SCHEMBL35210261 0.89 EGFR (0.66) EGFRALKEML4
SCHEMBL20548909 0.88 EGFR (0.47) EGFRALKEML4
SCHEMBL20548738 0.87 EGFR (0.49) EGFRALKEML4
SCHEMBL20548969 0.86 EGFR (0.54) EGFRALKEML4
SCHEMBL20548889 0.83 EGFR (0.68) EGFRALKEML4
SCHEMBL35210258 0.83 EGFR (0.68) EGFRALKEML4
SCHEMBL20549061 0.83 EGFR (0.48) EGFRALKEML4
SCHEMBL20548863 0.83 EGFR (0.46) EGFRALKEML4
SCHEMBL20548845 0.83 EGFR (0.46) EGFRALKEML4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3398939-B1 ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY ANCUREALL PHARMACEUTICAL SHANGHAI CO LTD (CN) 2026-05-06 EP claimed
EP-3398939-A1 ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY Ancureall Pharmaceutical (Shanghai) Co., Ltd. (CN) 2018-11-07 EP claimed
EP-3398939-B1 ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY ANCUREALL PHARMACEUTICAL SHANGHAI CO LTD (CN) 2026-05-06 EP disclosed
EP-3398939-A1 ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY Ancureall Pharmaceutical (Shanghai) Co., Ltd. (CN) 2018-11-07 EP disclosed