Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.54 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.54 |
| ▸ | DUS2 | Q9NX74 | 1/20 | 0.54 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | EML4 | Q9HC35 | 3/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20548937 | 0.93 | EGFR (0.49) | EGFRERBB3DUS2ERBB2EML4 | |
| SCHEMBL20548845 | 0.91 | EGFR (0.46) | EGFRERBB3DUS2EML4ALK | |
| SCHEMBL20548909 | 0.90 | EGFR (0.47) | EGFRERBB3DUS2EML4ALK | |
| SCHEMBL20548863 | 0.90 | EGFR (0.46) | EGFRERBB3DUS2EML4ALK | |
| SCHEMBL35210335 | 0.89 | EGFR (0.58) | EGFRERBB3DUS2EML4ALK | |
| SCHEMBL20548919 | 0.89 | EGFR (0.58) | EGFRERBB3DUS2EML4ALK | |
| SCHEMBL20549061 | 0.87 | EGFR (0.48) | EGFRERBB2KDREML4ALK | |
| SCHEMBL20548786 | 0.86 | EGFR (0.48) | EGFRERBB2KDREML4ALK | |
| SCHEMBL20548849 | 0.86 | EGFR (0.53) | EGFREML4ALK | |
| SCHEMBL20548788 | 0.84 | EGFR (0.45) | EGFRERBB3EML4ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3398939-A1 | ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY | Ancureall Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2018-11-07 | — | — | EP | disclosed |