Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F12 | P00748 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30872907 | 1.00 | ESR2 (0.45) | ESR2ADORA3RIPK2TLR8MAPT | |
| SCHEMBL17802507 | 0.88 | ESR2 (0.49) | ESR2ADORA3RIPK2TLR8MAPT | |
| SCHEMBL31457215 | 0.88 | ESR2 (0.49) | ESR2ADORA3RIPK2TLR8MAPT | |
| SCHEMBL29564697 | 0.87 | MKNK1 (0.46) | ESR2ADORA3TLR8ALDH1A1HPGD | |
| SCHEMBL19328774 | 0.87 | MKNK1 (0.46) | ESR2ADORA3TLR8ALDH1A1HPGD | |
| SCHEMBL17802466 | 0.84 | CYP19A1 (0.53) | ESR2ADORA3MAPTMAPK1ALDH1A1 | |
| SCHEMBL30872906 | 0.84 | CYP19A1 (0.53) | ESR2ADORA3MAPTMAPK1ALDH1A1 | |
| SCHEMBL31457231 | 0.84 | ESR2 (0.42) | ESR2ADORA3RIPK2TLR8MAPT | |
| SCHEMBL31375424 | 0.82 | MAPK1 (0.44) | ESR2ADORA3RIPK2TLR8MAPT | |
| SCHEMBL20548980 | 0.82 | ADORA3 (0.46) | ESR2ADORA3RIPK2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107635984-B | Heterocyclic substituted bicyclic azoles as pesticidal agents | FMC公司 | 2021-04-13 | — | — | CN | claimed |
| EP-3044220-B1 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | FMC CORP (US) | 2018-11-07 | — | — | EP | claimed |
| CN-112608300-B | Heterocyclic substituted bicyclic azole pesticides | FMC公司 | 2024-04-26 | — | — | CN | disclosed |
| EP-3424919-B1 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | FMC CORP (US) | 2022-04-27 | — | — | EP | disclosed |
| CN-112679467-A | Heterocyclic substituted bicyclic azoles as pesticidal agents | FMC公司 | 2021-04-20 | — | — | CN | disclosed |
| CN-107635984-B | Heterocyclic substituted bicyclic azoles as pesticidal agents | FMC公司 | 2021-04-13 | — | — | CN | disclosed |
| CN-112608300-A | Heterocyclic substituted bicyclic azoles as pesticidal agents | FMC公司 | 2021-04-06 | — | — | CN | disclosed |
| EP-3044220-B1 | HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES | FMC CORP (US) | 2018-11-07 | — | — | EP | disclosed |