Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 16/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.65 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20550218 | 0.86 | HDAC6 (0.53) | HDAC6HDAC1HDAC5HDAC4HDAC8 | |
| SCHEMBL20550193 | 0.82 | HDAC6 (0.55) | HDAC6HDAC1HDAC5HDAC4HDAC8 | |
| SCHEMBL18795728 | 0.80 | HDAC6 (0.47) | HDAC6HDAC1HDAC5HDAC4HDAC8 | |
| SCHEMBL22530719 | 0.79 | HDAC4 (0.57) | HDAC6HDAC1HDAC5HDAC4 | |
| SCHEMBL29392131 | 0.79 | HDAC4 (0.57) | HDAC6HDAC1HDAC5HDAC4 | |
| SCHEMBL20550150 | 0.79 | HDAC6 (0.57) | HDAC6HDAC1HDAC5HDAC4HDAC8 | |
| SCHEMBL19745335 | 0.79 | HDAC6 (1.00) | HDAC6HDAC1HDAC5HDAC4HDAC8 | |
| SCHEMBL20528665 | 0.79 | HDAC6 (0.65) | HDAC6HDAC1HDAC5HDAC4HDAC8 | |
| SCHEMBL20550314 | 0.78 | HDAC6 (0.64) | HDAC6HDAC1HDAC5HDAC4HDAC8 | |
| Hydrochloric Acid SCHEMBL20528676 | 0.78 | HDAC6 (0.63) | HDAC6HDAC1HDAC5HDAC4HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180319753-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180319753-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | PRF1, NOX1, ARG1 | HDAC6 610/4885HDAC1 551/4885HDAC5 1156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.