SCHEMBL20550348

SCHEMBL20550348

O=C1c2ccccc2NC1(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 4/20 0.52
GAA P10253 4/20 0.52
SI P14410 4/20 0.52
MGAM2 Q2M2H8 4/20 0.52
NTRK1 P04629 2/20 0.45
PRKD3 O94806 2/20 0.45
ABL1 P00519 2/20 0.45
CDK5 Q00535 2/20 0.45
DAPK3 O43293 1/20 0.45
MAP4K4 O95819 1/20 0.45
LCK P06239 1/20 0.45
FYN P06241 1/20 0.45
CSF1R P07333 1/20 0.45
RET P07949 1/20 0.45
PDGFRB P09619 1/20 0.45
PDGFRA P16234 1/20 0.45
LTK P29376 1/20 0.45
GRK5 P34947 1/20 0.45
KDR P35968 1/20 0.45
FLT3 P36888 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29396524 1.00 MGAM (0.52) MGAMGAASIMGAM2NTRK1
SCHEMBL29074194 0.92 MGAM (0.48) MGAMGAASIMGAM2NTRK1
SCHEMBL28417194 0.91 MGAM (0.48) MGAMGAASIMGAM2NTRK1
SCHEMBL28417192 0.87 MGAM (0.47) MGAMGAASIMGAM2NTRK1
SCHEMBL22890490 0.86 MGAM (0.43) MGAMGAASIMGAM2NTRK1
SCHEMBL29074193 0.82 GAA (0.50) MGAMGAASIMGAM2NTRK1
SCHEMBL28415732 0.81 STING1 (0.42) MGAMGAASIMGAM2NTRK1
SCHEMBL28415729 0.81 NTRK1 (0.44) MGAMGAASIMGAM2NTRK1
SCHEMBL29074192 0.79 MGAM (0.47) MGAMGAASIMGAM2NTRK1
SCHEMBL30923269 0.77 MGAM (0.43) MGAMGAASIMGAM2CDK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250191770-A1 COMPUTERIZED DECISION SUPPORT TOOL AND MEDICAL DEVICE FOR RESPIRATORY CONDITION MONITORING AND CARE PFIZER INC. (US) 2025-06-12 US claimed
WO-2023219526-A1 MULTITARGET ANTIVIRAL DIETARY SUPPLEMENT PROKIN MILAN (RS) 2023-11-16 WO claimed
US-20230329630-A1 COMPUTERIZED DECISION SUPPORT TOOL AND MEDICAL DEVICE FOR RESPIRATORY CONDITION MONITORING AND CARE PFIZER INC. (US) 2023-10-19 US claimed
WO-2023166453-A1 COMPUTERIZED DECISION SUPPORT TOOL AND MEDICAL DEVICE FOR RESPIRATORY CONDITION MONITORING AND CARE PFIZER INC. (US) 2023-09-07 WO claimed
EP-4203775-A1 COMPUTERIZED DECISION SUPPORT TOOL AND MEDICAL DEVICE FOR RESPIRATORY CONDITION MONITORING AND CARE Pfizer Inc. (US) 2023-07-05 EP claimed
WO-2022047311-A1 COMPUTERIZED DECISION SUPPORT TOOL AND MEDICAL DEVICE FOR RESPIRATORY CONDITION MONITORING AND CARE PFIZER INC. (US) 2022-03-03 WO claimed
US-12577240-B2 Antiviral heteroaryl ketone derivatives PFIZER INC. (US) 2026-03-17 US disclosed
US-12485157-B2 Method of treating COVID-19 PFIZER INC. (US) 2025-12-02 US disclosed
US-12358897-B2 Compounds and method of treating COVID-19 PFIZER INC. (US) 2025-07-15 US disclosed
US-20250191770-A1 COMPUTERIZED DECISION SUPPORT TOOL AND MEDICAL DEVICE FOR RESPIRATORY CONDITION MONITORING AND CARE PFIZER INC. (US) 2025-06-12 US disclosed
US-20250099424-A1 Nitrile-Containing Antiviral Compounds PFIZER INC. (US) 2025-03-27 US disclosed
EP-4516301-A2 NITRILE-CONTAINING COMPOUNDS FOR USE AS MEDICAMENTS Pfizer Inc. (US) 2025-03-05 EP disclosed
WO-2025037206-A1 DEUTERATED ANTIVIRAL COMPOUNDS PFIZER INC. (US) 2025-02-20 WO disclosed
WO-2022013684-A1 ANTIVIRAL HETEROARYL KETONE DERIVATIVES PFIZER INC. (US) 2022-01-20 WO disclosed
US-20220017548-A1 Compounds and Methods for the Treatment of COVID-19 PFIZER INC. (US) 2022-01-20 US disclosed
WO-2021250648-A1 NITRILE-CONTAINING ANTIVIRAL COMPOUNDS PFIZER INC. (US) 2021-12-16 WO disclosed
WO-2021176369-A1 METHODS OF INHIBITING SARS-COV-2 REPLICATION AND TREATING CORONAVIRUS DISEASE 2019 PFIZER INC. (US) 2021-09-10 WO disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12485157-B2 Method of treating COVID-19 ACE2, ACE, TMPRSS2 MGAM 279/4885GAA 293/4885SI 450/4885
US-12358897-B2 Compounds and method of treating COVID-19 ACE2, ACE, SARS1 MGAM 2529/4885GAA 1065/4885SI 3643/4885
US-12577240-B2 Antiviral heteroaryl ketone derivatives ACE2, SARS1, ACE MGAM 1880/4885GAA 1403/4885SI 3076/4885
US-20250099424-A1 Nitrile-Containing Antiviral Compounds ACE2, NOS2, EIF2AK2 MGAM 3437/4885GAA 2523/4885SI 3817/4885
US-20220017548-A1 Compounds and Methods for the Treatment of COVID-19 ACE2, ACE, SARS1 MGAM 2733/4885GAA 891/4885SI 3504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.