Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | SI | P14410 | 4/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | LTK | P29376 | 1/20 | 0.40 |
| ▸ | GRK5 | P34947 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29074193 | 0.80 | GAA (0.50) | MGAMGAASIMGAM2NTRK1 | |
| SCHEMBL20550348 | 0.79 | MGAM (0.52) | MGAMGAASIMGAM2NTRK1 | |
| SCHEMBL29396524 | 0.79 | MGAM (0.52) | MGAMGAASIMGAM2NTRK1 | |
| SCHEMBL18418508 | 0.75 | JAK2 (0.50) | MGAMGAASIMGAM2TP53 | |
| SCHEMBL29074194 | 0.75 | MGAM (0.48) | MGAMGAASIMGAM2NTRK1 | |
| SCHEMBL28417194 | 0.74 | MGAM (0.48) | MGAMGAASIMGAM2NTRK1 | |
| SCHEMBL28417192 | 0.73 | MGAM (0.47) | MGAMGAASIMGAM2NTRK1 | |
| SCHEMBL21430990 | 0.73 | JAK2 (0.48) | MGAMGAASIMGAM2NTRK1 | |
| SCHEMBL30159170 | 0.73 | JAK2 (0.48) | MGAMGAASIMGAM2NTRK1 | |
| SCHEMBL22890490 | 0.70 | MGAM (0.43) | MGAMGAASIMGAM2NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116751150-A | Synthesis method of 2-indolyl substituted indol-3-one compound | 福建医科大学 | 2023-09-15 | — | — | CN | disclosed |