Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.73 |
| ▸ | CDC25B | P30305 | 5/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | HPGD | P15428 | 2/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 2/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.73 |
| ▸ | ATM | Q13315 | 1/20 | 0.73 |
| ▸ | FADS1 | O60427 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL557025 | 0.93 | ALDH1A1 (0.66) | ALDH1A1CDC25BHSD17B10CYP3A4HPGD | |
| SCHEMBL29365372 | 0.93 | ALDH1A1 (0.66) | ALDH1A1CDC25BHSD17B10CYP3A4HPGD | |
| SCHEMBL17422012 | 0.92 | ALDH1A1 (0.61) | ALDH1A1CDC25BHSD17B10CYP3A4HPGD | |
| SCHEMBL9486043 | 0.91 | ALDH1A1 (0.81) | ALDH1A1CDC25BHSD17B10CYP3A4HPGD | |
| SCHEMBL29609502 | 0.89 | ALDH1A1 (0.92) | ALDH1A1CDC25BHSD17B10CYP3A4HPGD | |
| SCHEMBL4797443 | 0.89 | ALDH1A1 (0.92) | ALDH1A1CDC25BHSD17B10CYP3A4HPGD | |
| SCHEMBL11962223 | 0.88 | ALDH1A1 (0.69) | ALDH1A1CDC25BHSD17B10CYP3A4HPGD | |
| SCHEMBL28154822 | 0.88 | ALDH1A1 (0.63) | ALDH1A1CDC25BHSD17B10CYP3A4HPGD | |
| SCHEMBL4171779 | 0.88 | ALDH1A1 (0.59) | ALDH1A1CDC25BHSD17B10CYP3A4HPGD | |
| Diphenylamine SCHEMBL1072941 | 0.88 | ALDH1A1 (0.96) | ALDH1A1CDC25BHSD17B10CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190309289-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2019-10-10 | — | — | US | disclosed |
| US-10370654-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2019-08-06 | — | — | US | disclosed |
| US-20180320170-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2018-11-08 | — | — | US | disclosed |