Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 3/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | SCD | O00767 | 2/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | MTOR | P42345 | 3/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17778459 | 0.90 | GSK3B (0.38) | GRM5FAAHDYRK1AGSK3BTRPV1 | |
| SCHEMBL17769524 | 0.89 | GRM5 (0.36) | GRM5FAAHDYRK1AGSK3BMEN1 | |
| SCHEMBL17618589 | 0.89 | PIK3CA (0.41) | GRM5FAAHDYRK1ASCDPTPN11 | |
| SCHEMBL17769695 | 0.83 | WNT3A (0.38) | GRM5FAAHDYRK1AGSK3BTRPV1 | |
| SCHEMBL17778461 | 0.83 | WNT3A (0.38) | GRM5FAAHDYRK1AGSK3BTRPV1 | |
| SCHEMBL16754659 | 0.81 | GSK3B (0.35) | GRM5FAAHDYRK1APTPN11PIK3CA | |
| SCHEMBL16754479 | 0.80 | ABL1 (0.35) | GRM5FAAHDYRK1ASCDPTPN11 | |
| SCHEMBL17778498 | 0.80 | PHGDH (0.41) | FAAHTRPV1MEN1KMT2AHPGD | |
| SCHEMBL17769756 | 0.80 | TRPV1 (0.39) | GRM5FAAHPTPN11TRPV1MEN1 | |
| SCHEMBL19361186 | 0.79 | MTOR (0.41) | FAAHDYRK1ASCDPIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180319810-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2018-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180319810-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | SIRT1, SIRT3, SIRT2 | BMP1 4258/4885GRM5 3991/4885FAAH 1283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.