Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21484221 | 0.84 | MEN1 (0.41) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL28691331 | 0.78 | MEN1 (0.44) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL31498821 | 0.76 | NCF1 (0.50) | MEN1KMT2AMAPTALDH1A1NCF1 | |
| SCHEMBL1131286 | 0.76 | NCF1 (0.50) | MEN1KMT2AMAPTALDH1A1NCF1 | |
| SCHEMBL10511286 | 0.75 | HTT (0.63) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL10649068 | 0.75 | HTT (0.42) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL10767713 | 0.75 | ECE2 (0.42) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL1602780 | 0.75 | HTR1B (0.44) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL10675894 | 0.75 | MEN1 (0.41) | MEN1KMT2AMAPTHTTALDH1A1 | |
| Phosphine SCHEMBL23753735 | 0.74 | MAPT (0.49) | MEN1KMT2AMAPTALDH1A1NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3619197-A1 | TRISUBSTITUTEDSILYLMETHYLPHENOXYQUINOLINES AND ANALOGUES | Bayer Aktiengesellschaft (DE) | 2020-03-11 | — | — | EP | disclosed |
| CN-110582484-A | Trisubstituted silylmethylphenoxyquinolines and analogs thereof | 拜耳公司 | 2019-12-17 | — | — | CN | disclosed |
| CN-110582484-A | Trisubstituted silylmethylphenoxyquinolines and analogs thereof | 拜耳公司 | 2019-12-17 | — | — | CN | disclosed |
| CN-110582484-A | Trisubstituted silylmethylphenoxyquinolines and analogs thereof | 拜耳公司 | 2019-12-17 | — | — | CN | disclosed |
| WO-2018202712-A1 | TRISUBSTITUTEDSILYLMETHYLPHENOXYQUINOLINES AND ANALOGUES | BAYER AKTIENGESELLSCHAFT (DE) | 2018-11-08 | — | — | WO | disclosed |